Oncostatin K
Oncostatin K

Oncostatin K review

Oncostatin K is used to treat various types of cancer including testicular and sarcomas. It belongs to a group of cancer-fighting medicaments that inhibit the growth of cancer cells in the body.


Oncostatin K is available under the brand names Act-D and Actinomycin D and is commonly prescribed to children, but adults may also benefit from this medicament. Oncostatin K is for the treatment of cancers of the soft tissue and bones particularly tendons and muscles, tumors in the womb, and cancer of the testicles.


Oncostatin K is injected in a vein for about 15 minutes. Patients are often given a medicine prior to Oncostatin K to stop any vomiting or nausea once the medicament is administered.

The dosage of Oncostatin K depends on the affected role's size, blood count, condition and the cancer being treated. Blood counts are typically taken before treatment of Oncostatin K. If the lab tests indicate unsafe conditions, the treatment will be delayed.

It is typical for affected roles to take Oncostatin K with other chemotherapy dugs.


Oncostatin K can decrease the amount of white blood cells in the body for weeks, which can increase the affected role's risk of infection. Patients should immediately inform their physician if they experience symptoms of an infection including high fever, pain when urinating, chills, or coughs.

Oncostatin K can lower the platelet count of the affected role for a few weeks after treatment, increasing the affected role's risk of bleeding. Patients should notify their physician if they experience unexplained bleeding including nosebleeds, tarry stools, or bleeding gums.

There is a risk that Oncostatin K will decrease the number of red blood cells in the body. Anemia, a decreased red blood cell count, often results in difficulty in breathing, and exhaustion. Your physician may prescribe additional medicines to prevent this condition or you may need to have a blood transfusion.

Patients should not have any vaccinations while taking this medicament without the prior consent of their physician. Oncostatin K can affect a affected role's immune system and alter the effectiveness of vaccinations and can lead to severe infections.


Oncostatin K can result in baldness. However, this is a temporary side effect and the hair usually grows back after the treatment.

Patients should talk with their physician about their complete medical history, especially if they have had liver, kidney, heart diseases, diabetes, heart failure, gout, kidney stones, and infections. These conditions may require a change in the dosage of Oncostatin K.

Patients who have been treated with radiation are typically given decreased dosages of Oncostatin K.


This medicament can effect the fertility of affected roles. It can cause birth defects, especially if the mother took Oncostatin K during pregnancy or conception. Patients who are taking Oncostatin K should use birth control to lessen risks of conception.

Oncostatin k has the following structural formula:

Chemical structure of oncostatin k

 Molecular formula of oncostatin k is C62H86N12O16
 Chemical IUPAC Name is 8-amino-N-(2-amino-4,6-dimethyl-3-oxo-phenoxazin-1-yl)carbonyl-N'-[8-amino-4,6-dimethyl-7-oxo-9-[[3,6,10-trimethyl-7,14-bis(1-methylethyl)-2,5,8,12,15-pentaoxo-9-oxa-3,6,13,16-tetrazabicyclo[14.3.0]nonadec-11-yl]carbamoyl]phenoxazin-1-yl]carbonyl-4,6-dimethyl-7-oxo-N,N'-bis[3,6,10-trimethyl-7,14-bis(1-methylethyl)-2,5,8,12,15-pentaoxo-9-oxa-3,6,13,16-tetrazabicyclo[14.3.0]nonadec-11-yl]-1,9-bis[[3,6,10-trimethyl-7,14-bis(1-methylethyl)-2,5,8,12,15-pentaoxo-9-oxa-3,6,13,16-tetrazabicyclo[14.3.0]nonadec-11-yl]carbamoyl]phenoxazine-1,9-dicarboxamide
 Molecular weight is 1255.42 g/mol
 Oncostatin k available : 0,5mg injection

Generic name: Dactinomycin

Brand name(s): Cosmegen, Dactinomicina, Dactinomycine, Dactinomycinum, Lyovac Cosmegen, Meractinomycin, Oxamide

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