Pamelor is also prescribed as Aventyl HCI and is generically available as nortriptyline. Pamelor is a tricyclic antidepressant and is used in the treatment of depression.
Some patients undergo a period of worsening symptoms which make them agitated, irritable, angry, panicked, and filled with anxiety, subject to mood changes, aggressive, and filled with thoughts or intentions of harming themselves, someone else, or considering suicide. These symptoms may be temporary or long term, and are more likely to arise in patients less than 21 years of age. These symptoms should be closely monitored and the patient should be removed from the medication.
Not all patients will tolerate Pamelor well and a medical history should be thoroughly evaluated before this medication is prescribed for them. Patients with a medical history which includes heart attacks, heart disease, strokes, seizures, bipolar disorder, schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, and difficulty urinating may not be able to take Pamelor or may require careful monitoring while undergoing drug therapy with this medication, depending on the condition and the severity of the condition.
Pamelor should always be taken as it ahs been prescribed to avoid the potential for an overdose. An overdose is likely to occur either intentionally or if the patient takes a double dose to make up for a missed dose. If the dosage missed can be taken with enough time before the next regular dose, then it should be. Taking a dosage too close together with the next dose may cause an overdose. Overdosing requires medical attention at the nearest emergency room. Confusion, extreme drowsiness, fainting, convulsions, seizures, muscle stiffness, feeling very hot, feeling very cold, agitation, hallucination, blurry vision, vomiting, coma, and death are all symptoms an overdose is likely to present.
Patients should avoid drinking alcohol while taking Pamelor. Medication that are likely to make a patient sleepy should not be taken along with Pamelor including but not limited to cold medicine, anxiety relievers, muscle relaxants, analgesics, sedatives, seizure medications, or additional antidepressants. Grapefruit and grapefruit juice may cause negative interaction as well.
Side effects may be severe or mild, however severe side effects require immediate medical attention and the patient should seek help at the closest emergency facility. Side effects such as fast hear rate, pounding heart, uneven heart rate, chest pain, chest heaviness which includes the arm, sweating and generally feeling ill, sudden numbness or weakness that dominates one side of the body, sudden headache with confusion or problems with speech and vision, confusion, hallucination, convulsions, easy bruising or unexplained bleeding, tremors, restless muscle movements or muscular twitching especially in the jaw, eyes, neck, or tongue, extreme thirst accompanied by a headache, nausea, vomiting, and weakness, lightheadedness, fainting, and a decrease or inability to urinate are considered severe and require immediate emergency attention. Facial swelling (swelling of the lips, mouth, tongue, or throat, hives, and difficulty breathing) is an indicator of an allergic reaction and requires immediate medical attention.
Nausea, vomiting, stomach pain, loss of appetite, constipation, diarrhea, changes in weight, unpleasant taste in the mouth, dry mouth, loss of coordination, weakness, numbness, tingles, anxiousness, restlessness, insomnia, nightmares, blurry vision, headaches with ringing in the ears, mild skin rashes, breast swelling in both men and women, and an increase in sweat production are considered mild side effects and may be reduced by lowering the dosage of medication.
Pamelor should not be taken with cimetidine, guanethidine, reserpine, or heart rhythm medication or any other antidepressants. Patients should always contact their doctor before taking any mew medications, including over the counter medicines and herbal supplements or vitamins.
Pamelor has the following structural formula:
• Molecular formula of pamelor is C19H21N
• Chemical IUPAC Name is 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
• Molecular weight is 263.377 g/mol
• Pamelor available : 25mg capsules, 10mg capsules, 50mg capsules, 75mg capsules, 10mg/5ml solution
Generic name: Amitriptyline
Brand name(s): Adepress, Adepril, Amineurin, Amitid, Amitril, Amitriprolidine, Amitriptylin, Amitryptiline, Amitryptyline, Amytriptiline, Damilan, Damilen, Damitriptyline, Elanil, Elavil, Endep, Flavyl, Hexathane, Horizon, Lantron, Laroxil, Laroxyl, Lentizol, Proheptadiene, Redomex, Saroten, Sarotex, Seroten, Sylvemid, Triptanol, Triptilin, Triptisol, Tryptanol, Tryptizol
Review published on: 17 May 2007
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