Panoral review

Panoral, a second-generation broad-spectrum antibiotic from the antibacterial medications known as cephalosporins, is available by the brand names Ceclor, Ceclor CD, Ceclor Pulvules, and Raniclor.

Panoral is for bacterial infections like pneumonia, and infections of the ear, lung, skin, throat, and urinary tract. It works by penetrating the body's tissues and fluids, and stopping the growth of the bacteria causing the infection.

Panoral should not be given to patients who are allergic to cephalosporin, penicillin or other antibiotics. If they have a kidney disorder or any digestive illness like colitis, patients should tell their physician of these illnesses and get a prescription for a different dosage and be monitored during treatment.

The suspension liquid of Panoral contains sucrose and is not advisable for diabetics. Pregnant women and women planning to become pregnant should talk with their physician before taking this medication. Panoral can be passed through breast milk. Nursing mothers need to tell their physician if they are breastfeeding before taking the medication, so as not to harm a nursing infant.

Patients should not take antacids that contain magnesium or aluminum while taking Panoral as these can lower the efficacy of the antibiotic. These include Rolaids, Maalox, Mylanta, and Milk of Magnesia. Other medications known to interact with Panoral include Warfarin (an anticoagulant), Probenecid (an arthritis and gout medication), loop diuretics or water pills, and other antibiotics. Patients should inform their physician of any prescription or over-the-counter medications, vitamins or herbal supplements they are taking prior to starting Panoral treatment.

Known side effects include allergic reactions in the form of rashes, itching, uticaria (hives), fever, serum sickness-like reactions (hypersensitivity), arthralgia (joint pain), and anaphylaxis (whole body atopy). Some patients may experience diarrhea, nausea, vomiting, stomach upset, transient hepatitis, jaundice, headaches and Stevens-Johnson syndrome (a deadly allergic skin illness). In rare cases, blood disorders, nephritis (kidney inflammation), hyperactivity, nervousness, disrupted sleep, hallucinations, confusion and dizziness have occurred.

Patients should stop taking Panoral and seek emergency medical attention if they experience severe allergic reactions including breathing difficulties, swelling of the facial tissue, rashes, redness or itching, nausea, vomiting or diarrhea, blood or mucus in their stools, or unexplained bleeding and bruising. Any side effect experienced by the patient should be reported to their physician, particularly if it interferes with day-to-day activities.

Panoral is available in purple and white 250 mg. capsules, purple and gray 500 mg. capsules, and as a suspension (liquid) in strawberry flavor. Ceclor CD is manufactured in blue tables of 375 and 500 mgs. When taking Panoral in liquid suspension, the bottle needs to be shaken and the correct dosage accurately measured using a measuring spoon or cup.

Panoral is to be taken with a full glass of water on a full or empty stomach. Ceclor CD, in extended release capsules, should be taken with food or milk to prevent an upset stomach. Ceclor CD pills are made so the medicine is released slowly into the body, so it is advisable not to cut, grind or chew them.

While symptoms of an infection often disappear quickly, the bacteria causing the infection may still remain in the body. Cutting the medication process short may cause the body to develop a resistance to the antibiotics.

Panoral needs to be taken regularly for the prescribed period to make sure the body maintains a consistent level of the medication, and to obtain the best results. Any unused medication should be disposed of after 14 days.

Panoral has the following structural formula:

Chemical structure of panoral

• Molecular formula of panoral is C15H14ClN3O4S
• Chemical IUPAC Name is (6R,7R)-7-[(2-amino-2-phenylacetyl)amino]-3-chloro-8-oxo- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Molecular weight is 367.8074 g/mol
Panoral available : 250mg capsules, 500mg capsules, 187mg/5ml suspension 100ml bottle, 375mg/5ml suspension 100ml bottle, 125mg/5ml suspension 150ml bottle, 250mg/5ml suspension 150ml bottle, 187mg/5ml suspension 50ml bottle, 375mg/5ml suspension 50ml bottle, 125mg/5ml suspension 75ml bottle, 250mg/5ml suspension 75ml bottle

Generic name: Cefaclor

Brand name(s): Alenfral, Alfacet, Alfatil, Ceclor, Ceclor CD, Cefaclorum, Cephaclor, Distaclor, Kefral, Panacef, Raniclor

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