GERD or gastroesophageal reflux disease is mostly responsible for the damage in the esophagus
and the stomach
. Chronic symptoms of disturbance may occur if the disease is not treated. It may even be responsible for the development of other conditions.
The abnormal reflux in the esophagus caused by GERD
may sometimes bring on ulcers. For this kind of case, proton pump inhibitor drugs like Pantoprazole
Pantoprazole may be used either as a short-term or long-term treatment for the effects of GERD. It can be used as an eight-week treatment for erosion and ulceration of the esophagus or as a maintenance therapy drug for the same purpose. Pantoprazole is also used in other conditions involving overproduction of stomach acid.
An increased production of acid may interfere with the ability of the stomach and the esophagus to heal. This is the main course of action that Pantoprazole takes. By reducing the stomach acid produced, it paves the way for a damage to heal easier.
The German chemical company, Altana, developed Pantoprazole. Different pharmaceutical companies market it worldwide under the brand names Protonix
, Somac, Astropan, Pantor, Pantoloc, Protium, and TopZole. No generic formulation for Pantoprazole is available.
Like with the use of other prescription medicines, health concerns must be raised prior and during Pantoprazole treatment.
The class of proton-pump inhibitors is contraindicated to patients that may develop allergic reactions
against the drug. It is also not advisable to use for pregnant and lactating mothers. Although actual effects of Pantoprazole on unborn and newborn babies have not yet been established, it is mostly advisable for any pregnant or lactating woman to take precaution before taking any drug, prescription, or otherwise. Pantoprazole is less likely to attract drug interactions. A doctor’s monitoring about the use of other drugs alongside this treatment, however, is still advised.
Patients using Pantoprazole as a treatment must be aware that concentrations of the drug in the bloodstream may interfere with the results of certain clinical tests. Before undergoing any kind of lab test, you must inform your doctor about your Pantoprazole use. Other side effects of the drug must also be taken up thoroughly with your doctor to ensure that your symptoms do not cause alarm. Pantoprazole may cause constipation
, skin rash, and headaches
. These adverse effects are temporary. If your symptoms persist or worsen, you must call your doctor immediately.
Pantoprazole use is usually directed once or twice every day for a certain period. You must remember to take your medicine on schedule to ensure its efficiency. For maximum effect, avoid taking Pantoprazole close to meal time.
Other concerns about Pantoprazole use shall be discussed by your doctor based on the results of your examinations. It is important that you follow the doctor’s prescription carefully to ensure that you will get the maximum benefit from the medicine treatment. Following the prescription will also lessen your risks for unsightly effects. Make a regular visit to your doctor during treatment to ensure that your body’s responses to the medicine is closely monitored.
Pantoprazole has the following structural formula:
• Molecular formula of pantoprazole is C16H15F2N3O4S
• Chemical IUPAC Name is 5-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-3H-benzoimidazole
• Molecular weight is 383.371 g/mol
• Pantoprazole available : 20mg tablets, 40mg tablets