Penicillin review

A long time ago in 1928, a Scottish biologist named Sir Alexander Fleming was surprised to find that the bacteria colony of Staphylococcus areus that he was cultivating in a dish was slowly being destroyed by a type of mold. The mold was called Penicillium notatum, and Sir Alexander Fleming became the first to discover the antibacterial properties of what would later become penicillin, the world’s first antibiotic.

It was decades later in the 1940’s when two other scientists, Howard Florey and Ernst Chain tested Sir Alexander’s discovery by injecting the Penicillium notatum into mice with infectious bacteria. The mice recovered and lived, proving that the mold had strong anti-bacterial powers. Florey and Chain extracted the active ingredient of Penicillium notatum and developed it into a medicine in powder form.

The discovery and use of penicillin can be considered a great breakthrough in the history of medicine. For the first time, a remedy was available to destroy germs and kill bacteria, enabling the human body to survive an infection. Penicillin was used during World War II to treat wounded soldiers, and it has saved many other lives as well.

In general, penicillin is used to treat infections that are caused by bacteria. It works by killing off the bacteria and preventing it from growing back. As there are different kinds of infections, there are also different kinds of penicillin to treat them. There are currently 20 types of penicillin to treat bacterial infections that affect the different parts of the body.

Penicillin has been used to lessen the frequency of a various kinds of infectious diseases like pneumonia, tuberculosis and diphtheria. It can also prevent infections that may contaminate the body after open heart surgery, organ transplants or treatment of serious burns. If you have ear, nose or throat infections, urinary tract or respiratory infections, infections that affect the prostate and even some sexually transmitted diseases, penicillin is an effective drug to use.

PenicillinV is a brand name for penicillin. It can be taken after meals or on an empty stomach. Following your doctor’s exact instructions or the directions on the label of your prescription is recommended.

Penicillin can come in liquid, tablet or the injectible form of the medication. If you are taking penicillin in liquid form, measure the exact dose using a measuring spoon or medicine cup. While undergoing treatment, it is advisable to have periodic blood tests to make sure that the penicillin is actually helping you get better.

Before starting your penicillin therapy, inform your doctor if you are allergic to the drug, on a low-salt diet, pregnant or breastfeeding, and taking other medication that can interfere with the effects of penicillin or cause serious side-effects. If you have other medical problems like asthma, a history of bleeding problems or heart failure, cystic fibrosis and kidney ailments, you should tell your doctor as well, so your penicillin dosage can be adjusted. You are likely required to take some tests to determine whether penicillin is safe for you to take.

When you are taking penicillin, expect to experience the accompanying side-effects which include headaches, stomachaches, nausea and vomiting, itching in the vaginal region, a swollen tongue or even thrush (white patches that appear in the mouth or throat). If you suddenly develop hives, bloody diarrhea, fever and chills, swelling in the face and mouth, weakness, bleeding and bruising, confusion or seizures, these are serious side-effects which will need immediate medical attention.

Penicillin is the forerunner of the modern antibiotic. Without the discovery of that first wonder drug, penicillin, it is doubtful that we would have been able to develop all the different types of antibiotics that effectively treat infection today.

Penicillin has the following structural formula:

Chemical structure of penicillin

• Molecular formula of penicillin is C16H18N2O5S
• Chemical IUPAC Name is 3,3-dimethyl-6-oxo-7-(2-phenoxyacetyl)amino-2-thia-5- azabicyclo[3.2.0]heptane-4-carboxylicacid
• Molecular weight is 350.391 g/mol
Penicillin available : 250mg/5ml solution, 250mg tablets, 500mg tablets

Brand name(s): Abbocillin, Acipen V, Apopen, Ayercillin, Beepen-Vk, Benzopenicillin, Benzylpenicillin, Beromycin, Betapen-Vk, Bicillin, Calcipen, Cillora, Cilloral, Cilopen, Compocillin V, Cosmopen, Crystapen V, Distaquaine V, Dropcillin, Eskacillian V, Eskacillin V, Fenacilin, Fenospen, Fenoxypen, Galofak, Gelacillin, Kenyan, Ledercillin Vk, Liquacillin, Longisil, Magnus, Medivit, Megacillin, Meropenin, Oml, Oracillin, Oratren, Ospen, Pedikleen, Pen-Oral, Pen-V, Pen-Vee, Penapar-Vk, Pencillin G, Pendamine, Pentids, Permapen, Pfizerpen, Pfizerpen G, Pfizerpen Vk, Pfizerpen-As, Pharmacillin, Phenocillin, Phenomycilline, Phenopenicillin, Pradupen, Robicillin, Rocilin, Specilline G, Stabicillin, Starbien, Sterol, Ursopen, Uticillin Vk, V-Cil, V-Cillin, V-Cillin K, V-Cylina, V-Cyline, V-Tablopen, Vebecillin, Veetids, Wycillin

  Your Penicillin review