Plavix is generically prescribed as clopidogrel. It is most commonly prescribed to assist in the prevention of blood clots, particularly in patients who have had a recent heart attack, stroke, or the symptoms and warning signs of a heart attack or stroke. In rare cases, Plavix may be used for patients who are in need of a blood thinner after surgery but are unable to take Coumadin for some reason. The goal of Plavix is to prevent the blood’s platelets from clotting in the veins and arteries.
Patients who are taking Plavix need to be extremely cautious when they have acquired even a minor cut. Plavix can accelerate bleeding, even internal bleeding, and all accidents no matter how minor require a physician’s assistance to prevent problems related to bleeding.
Other side effects may occur when taking Plavix, and some may require urgent medical attention. Patients who experience an allergic reaction, such as difficulty breathing, hives, itching, and swelling of the facial features, tongue, or throat need to acquire immediate medical assistance. Other serious side effects that require immediate emergency medical care include stools that are black, bloody, or tarry, nosebleeds, bleeding that will not stop, coughing up blood, vomiting a coffee ground like material, a sudden sensation of numbness or weakness that dominates on side of the body, symptoms of a heart attack (chest pain, heaviness in the chest, pressure running down the arm, difficulty breathing, and generally feeling ill,) easy bruising, paleness of the skin, a significant change in urination habits, weakness, or a sudden onset headache with confusion and problems with speech or vision.
Less serious side effects generally do not require emergency medical assistance but should definitely be reported to the prescribing physician as soon as possible for evaluation. Symptoms such as a mild headache, sore throat, cough, runny nose, dizziness, or stomach pain are generally not considered threatening, but may be able to be reduced with the help of the prescribing physician.
Not all patients can tolerate Plavix. Patients should be clear about their medical history before starting this or any medication. Patients with a medical history of hemophilia or other bleeding or clotting disorder, stomach ulcer, liver disease, ulcerative colitis, kidney disease, stroke, or TIA should not take Plavix without extreme caution and careful monitoring.
According to the American Food and Drug Administration, women who are pregnant should not anticipate any prenatal affect, as this medication is rated a category B pregnancy risk. There is insufficient evidence to determine whether or not Plavix has any ill effect on a nursing infant, and this medication should be avoided for women who are nursing.
Patients should follow the instructions provided by the pharmacist when taking Plavix. If the patient should miss a dose, the dose should be taken when remembered. If the time for the next regular dose is nearing, then the missed dose should be skipped and regular dosing resumed at the next dose. Patients should never take additional medicine to make up for a missed dose, nor should they take their doses too close together. Doing so may result in an overdose.
An overdose requires immediate emergency medical care. Symptoms of an overdose are likely to include exhaustion, shortness of breath, difficulty breathing, vomiting, bloody stools, and blood in the vomit.
Patients should never mix medications without the prescribing physician’s consent. This includes prescription, over the counter, and herbal medications and remedies. Patients should also discuss their vitamin supplements with their physician. Medication with known interactions with Plavix include Dilantin, Lescol, Orinase, Nolvadex, Demadex, blood thinners, medications which prevent blood clots, aspirin, or other NSAID pain relievers.
Plavix has the following structural formula:
• Molecular formula of plavix is C16H16ClNO2S
• Chemical IUPAC Name is methyl (2S)-2-(2-chlorophenyl)-2-(9-thia-4-azabicyclo[4.3.0]nona-7,10-dien-4-yl)acetate
• Molecular weight is 321.822 g/mol
• Plavix available : 75mg tablets
Generic name: Clopidogrel
Review published on: 26 October 2007
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