Pravidel review

Pravidel, an ergoline derivative, causes vasoconstriction or a narrowing of the blood vessels. It is also a dopamine agonist that works by activating dopamine receptors in the brain for effective use against pituitary tumors and Parkinsons disease.

Pravidel is also used in the treatment of amenorrhea (a female condition where the menstrual period fails to occur). It is further used for infertility, abnormal breast milk discharge, hypogonadism (male reproductive disorder of the gonads), and acromegaly (excessive growth hormones in the body).

The medication works by lowering the body's levels of prolactin, the hormone primarily responsible for fertility and breast milk production in women. Since its prolactin content stimulates the immune system's T-lympocytes, Pravidel can be used to inhibit the immune system of patients undergoing organ transplants.

Pravidel also reduces the levels of hormonal growth in the body. It mimics the action of dopamine, a naturally occurring chemical in the body. This makes it ideal for the treatment of Parkinson's disease, a condition characterized by low dopamine levels in the brain, including its accompanying symptoms of stiffness, spasms, tremors and poor muscle control.

Other uses of Pravidel include treatment of cocaine addiction and neuroleptic malignant syndrome, a condition where tumors occur.

Before undergoing Pravidel therapy, inform your physician if you are allergic to this or any other medication, particularly erythromycin, levodopa, hypertension medicines, medicaments for cephalalgias or depression, decongestants, albuterol, terbutaline, oral contraceptives, tranquilizers, and any vitamin, mineral or herbal supplement.

Patients with kidney, heart or liver disease, a history of myocardial infarction, angina (chest pain), any incidence of mental illness or circulatory problems in the fingers during cold weather should tell their physician of these conditions before starting Pravidel treatment. These conditions may require a lower dosage of medication or constant monitoring during the course of treatment.

The effects of Pravidel are negated by phenothiazine medicaments like chloropromazine, thioridazine, mesoridazine, perphenazine and fluphenazine. These may require an increase in Pravidel dosage.

Patients should let their physician know if they are pregnant, plan to become pregnant or become pregnant during treatment. Although Pravidel has been classified in pregnancy Category B, which makes it unlikely to be harmful to the fetus, Pravidel should only be taken if the benefits far outweigh any potential risk it may pose to an unborn baby. Since Pravidel can stop lactation, breastfeeding is not encouraged while undergoing treatment.

Women taking Pravidel who do not wish to become pregnant, will need to use a different method of birth control other than oral contraceptives, as this may cause delays in the menstrual period.

Since Pravidel can cause low blood pressure and somnolence, patients taking this medication should refrain from sitting up or rising abruptly, driving a vehicle, operating any type of machinery or consuming alcoholic beverages, which may exacerbate dizziness and lightheadedness.

If patients are taking the medication for the treatment of high levels of prolactin that are caused by tumors, they should let their physician know immediately if they start experiencing consistent watery nasal discharges.

Pravidel can cause mild temporary side effects as the body adjusts to the medication; however, patients should inform their physician if they start to experience severe or persistent side effects, including dizziness, stomach upset, cephalalgias, nasal congestion, fatigue, insomnia, vomiting or constipation. More serious side effects include tingling and swelling of feet or ankles, bloody vomit, fainting, nightmares, fast or irregular heartbeat, confusion, involuntary twitching movements, vision changes, depression, and a watery nasal discharge. If you experience any of these conditions, seek immediate medical attention.

Pravidel is manufactured under the brand name Parlodel, and is available by prescription in 2.5mg round white tablets and 5mg white caramel capsules. It should be taken as directed by the physician, usually several times a day with meals, depending on the patient's condition. Patients should not suddenly stop taking Pravidel without talking with their physician, as immediate cessation of the medication may make their condition worse.

Pravidel has the following structural formula:

Chemical structure of pravidel

• Molecular formula of pravidel is C32H40BrN5O5
Pravidel available : 5mg capsules, 2.5mg tablets

Generic name: Bromocriptine

Brand name(s): Alti-Bromocriptine, Apo-Bromocriptine, Bagren, Parlodel

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