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Protonix

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Protonix

Protonix review





Protonix, generically known as pantoprazole, is used as a short term treatment in healing and symptomatic relief from gastroesphageal reflux disease (GERD) and as a long term treatment pathological hypersecretory conditions, including Zollinger-Ellison syndrome. Protonix decreases the amount of acid the stomach can produce. It is a member of the family of medications known as proton pump inhibitors.

When taking this mediciation, regulated lab tests are important to monitor the patient’s response to Protonix. It is not a requirement to take the drug with food, unless an upset stomach occurs when taking Protonix. Patients should take this medication as directed by their health care provider. It should not only taken at the time of discomfort. The tablet should never be split, chewed or crushed. Any over the counter medication, dietary supplements or herbal medicines should be taken without the knowledge of the prescribing physician. The prescribing physician should only prescribe Protonix after a thorough medical assessment.

If a dose is missed, take the next dose as soon as possible. If it is close to the next schedule dose, then take the missed dose but do not take additional medication to compensate for the missed dose and never take two doses at once. Taking too much medication may lead to an overdose. Any patients taking ketoconazole should take it two hours prior to taking Protonix.

Women that are pregnant or breastfeeding should notify the health care provider. Protonix has the pregnancy rating category of B, which in this case means that there is no evidence that this medication will cause harm to an unborn fetus. It is undetermined whether the drug can be excreted when breastfeeding. Caution needs to be used when prescribing Protonix to Asian patients, side effects can be more severe in Asian patients. Protonix should not be prescribed to children because the safety and efficacy has not been determined yet. There are no known precautions that are necessary when prescribing Protonix to the elderly. Protonix may interfere with certain lab tests; notify physician or lab center prior to taking tests.

Some medications do have interactions with Protonix. Any drugs depending on gastric pH for bioavailability (ampicillin, cyancobalamin, ketoconazole and iron salts) are effected by Protonix by their absorption rate. This medication cannot be taken by patients that are taking an HIV protease inhibitor. The side effects of anticoagulants or diogoxin may be increased if taken with Protonix. Clarithromycin and voriconazole may increase the side effects of Pronotix.

Some medical conditions may have interactions when taking Protonix. Anyone with allergies to food and medicines may not tolerate taking Protonix. Any patients with liver problems or stomach or bowel cancer may not be able to take this medication. The health care provider should be notified if the patient has low amount of zinc in their blood. A thorough examination is recommended before taking this medication.

Diarrhea, headache, nausea, vomiting and stomach pain are common side effects of taking Protonix; if any of these should occur, contact the prescribing physician immediately. If severe side effects should occur, seek emergency medical attention. Severe allergic reactions (swelling of face, lips, throat or tongue) rash, hives, difficulty breathing, fever, chills, blistered or peeling skin, excessive bleeding or bruising, vision impairment or yellowing of skin and eyes are all the symptoms of severe side effects.

Protonix has the following structural formula:

Chemical structure of protonix


• Molecular formula of protonix is C16H15F2N3O4S
• Chemical IUPAC Name is 5-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-3H-benzoimidazole
• Molecular weight is 383.371 g/mol
Protonix available : 20mg enteric coated tabs, 40mg enteric coated tabs

Generic name: Pantoprazole

Brand name(s): Pantoloc, Pantoprazol, Pantoprazolum, Pantoprozole

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