Ranitidine HCL, which is also prescribed as Zantac, is commonly used to decrease acid in the stomach which leads to indigestion, heartburn, and gastroesophageal reflux disease. Ranitidine is a member of the family of medications known as histamine 2 blockers. It may take as long as eight weeks before the patient notices a significant decrease in symptoms.
Ranitidine HCL is not appropriate for everyone. A thorough medical history should be assessed prior to prescribing this medication. Patients with a medical history which includes porphyria, liver disease, or kidney disease may not be able to take this medication or may require careful monitoring while undergoing drug therapy with ranitidine HCL, depending on the condition and the severity of the condition.
The American Food and Drug Administration rated ranitidine HCL as a pregnancy risk category B. Ranitidine HCL is not expected to cause harm or birth defects in unborn babies. This medication does pass through the mother’s breast milk and may affect a nursing infant. The prescribing physician should discuss whether or not the benefits outweigh the risks prior to prescribing this medication to a pregnant or nursing woman.
There is a risk of side effects associated with ranitidine HCL, some of which are severe. A patient who is experiencing a serious side effect or an allergic reaction should seek immediate emergency medical attention. An allergic reaction will present with side effects such as facial swelling, including swelling of the lips, mouth, tongue, or throat, hives, and difficulty breathing. Other serious side effects which require emergency medical attention include symptoms such as fast heart rate, slow heart rate, chest pain or heaviness that includes the arm, coughing up green or yellow mucous, shortness of breath, unusual weakness, vision problems, unusual bleeding, easy bruising, fever, sore throat, headache with severe or blistering skin rash, stomach pain nausea, loss of appetite, dark urine, clay colored stools, and jaundice.
Other less serious side effects typically do not require immediate emergency medical attention but should be reported to the prescribing physician. Patients should be encouraged to report all side effects. Less serious side effects include symptoms such as insomnia, headache, dizziness, drowsiness, swollen or tender breasts, nausea, vomiting, stomach pain, diarrhea, constipation, or sexual dysfunction. Less serious side effects can often be reduced to a more tolerable level by reducing the dosage of ranitidine HCL.
Ranitidine HCL should be taken exactly as it has been prescribed by the physician. If the patient misses a dose, the dose should be taken as soon as it is remembered. However, if it is almost time for the next scheduled dose, the missed dose should be skipped to avoid the potential for an overdose. The patient should never take a double dose of this medication. If an overdose is suspected, the patient should seek immediate emergency medical attention. An overdose will present with symptoms which include loss of coordination or balance, lightheadedness, fainting, and stomach pain.
There is a risk of negative drug interactions associated with ranitidine HCL. A thorough medical history should be understood prior to prescribing this medication. Patients should be urged to inquire with the prescribing physician before taking any new medications, including over the counter medications and herbal remedies. Medications that have a known interaction with ranitidine HCL include triazolam, antacids, and medications that irritate the stomach such as ibuprofen.
Ranitidine hcl has the following structural formula:
• Molecular formula of ranitidine hcl is C13H22N4O3S
• Chemical IUPAC Name is N'-[2-[[5-(dimethylaminomethyl)-2-furyl]methylsulfanyl]ethyl]- N-methyl-2-nitro-ethene-1,1-diamine
• Molecular weight is 314.405 g/mol
• Ranitidine hcl available : 15mg/ml syrup, 150mg tablets, 300mg tablets
Generic name: Ranitidine
Brand name(s): Alquen, Alvidina, Artomil, Azuranit, Digestosan, Ergan, Esofex, Fendibina, Gastrial, Gastridina, Gastrolav, Gastrosedol, Kuracid, Label, Lake, Logat, Melfax, Microtid, Mideran, Neugal, Noctone, Noktome, Normon, Novo-Radinine, Nu-Ranit, Pep-Rani, Ptinolin, Quadrin, Quantor, Radin, Ran Lich, Rani 2, Rani AbZ, Rani-BASF, Rani-nerton, Rani-Puren, Rani-Q, Rani-Sanorania, Raniben, Raniberl, Raniberta, Ranibloc, Ranic, Ranicux, Ranidil, Ranidin, Ranidine, Ranidura, Ranifur, Ranigasan, Ranigast, Ranigen, Ranilonga, Ranimerck, Raniogas, Raniplex, Ranisan, Ranitab, Ranitic, Ranitidin, Ranitidin AL, Ranitidin Arcana, Ranitidin Atid, Ranitidin AWD, Ranitidin Basics, Ranitidin Duncan, Ranitidin Dyna, Ranitidin Helvepharm, Ranitidin Heumann, Ranitidin Hexal, Ranitidin Merck, Ranitidin Millet, Ranitidin NM, Ranitidin Normon, Ranitidin PB, Ranitidin Stada, Ranitidin von ct, Ranitidin-Cophar, Ranitidin-Isis, Ranitidin-ratiopharm, Ranitidina Tamarang, Ranitiget, Ranitin, Ranitine, Ranobel, Rantacid, Ranuber, Raticina, Regalil, Renatac, Rozon, Rubiulcer, Santanol, Serviradine, Sostril, Tanidina, Taural, Terposen, Toriol, Trigger, Tritec, Ulcecur, Ulcex, Ulcirex, Ulcodin, Ulcolind Rani, Ulcosan, Ulsaven, Ultidine, Viserul, Zandid, Zantac, Zantarac, Zantic
Review published on: 15 March 2007
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