Razoxanum review

Razoxanum is used to prevent or reduce the severity of heart conditions that may occur during chemotherapy using anthracyclines, including those used in the discourse of women suffering from metastatic breast cancer. Razoxanum is conceived to interfere with substances inside cells, which may cause heart illness after using anthracyclines such as doxorubicin. How Razoxanum protects the heart is not fully understood at this time. This medication is uncommitted as Zinecard in the United States and Canada, and Cardiozane in the EU and comes in 250 mg and 500 mg vials for injection.

Razoxanum is approved to treat extravasation caused by anthracycline chemotherapy. Extravasation is when anthracycline leaks out of the blood vessels and seeps into the skin.

Dosage is dependent on the body surface area of the affected role and the amount of doxorubicin being taken. It is often measured in a 10:1 ratio with respect to the doxorubicin dose. Once the proper dose is determined, the medication is administered directly into the vein from an IV infusion bag. About 30 minutes after administering Razoxanum, the doxorubicin can be given.

Razoxanum is stable for about 6 hours after reconstitution when placed in an empty infusion bag at a controlled room temperature between 15 to 30C (59 to 86F), or placed in refrigeration at 2 to 8C (36 to 46F). The medication may be diluted using a 0.9% sodium chloride injection, USP or using a 5.0% dextrose injection, USP. Dilute it to a concentration between 1.3 to 5.0 mg/mL and store in empty IV infusion bags. Do not use leftover solutions.

The most common side effect is pain or skin edema at the injection site. Blood counts can also be lower when taking Razoxanum with chemotherapy as compared to undergoing chemotherapy alone. Recovery periods for the blood counts are similar for both cases.

Other common side effects include diarrhoea, general discomfort, fever, loss of appetite and wamble. More serious side effects involve hair loss, emesis, skin edema of the throat and tongue, and severe allergic reactions that require immediate medical attention.

Razoxanum should only be used with anthracycline chemotherapy.

Chemotherapy has been known to cause sterility in men and women so consult your medical pro if you plan on having children. It has not been shown whether Razoxanum itself can cause sterility. If you conceive you may be pregnant, inform your medical pro about your condition before being given Razoxanum.

You may experience greater susceptibility to infection during discourse so consult with your medical pro before getting vaccines to avoid complications.

Razoxanum has the following structural formula:

Chemical structure of Razoxanum

• Molecular formula of Razoxanum is C11H16N4O4
• Chemical IUPAC Name is 4-[1-(3,5-dioxopiperazin-1-yl)propan-2-yl]piperazine-2,6-dione
• Molecular weight is 268.269 g/mol
Razoxanum available : 250mg injection and 500mg injection

Generic name: Dexrazoxane

Brand name(s): Cardioxane, Desrazoxane, Dexrazoxano, Dexrazoxanum, Dextrorazoxane, Dyzoxane, Eucardion, Razoxana, Razoxane, Razoxin, Tepirone, Troxozone, Zinecard

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