Reglan review

Reglan, generically known as metoclopramide, is a drug used to relieve symptoms associated with acute and recurrent diabetic gastro paresis, documented gastro esophageal reflux disease (GERD) that cannot be treated by conventional methods. Reglan is used to stimulate the upper GI tract that results in accelerated gastric emptying and intestinal transit and increased resting tone of lower esophageal sphincter. Its less common uses are: the prevention of nausea and vomiting in cancer patients receiving chemotherapy. It is sometimes used as a treatment for hiccoughs and migraines. It has been proven to stimulate lactation in slow to produce mothers. This medication is often used when taking x-rays of a patient’s stomach or intestinal tract.

Prior to taking Reglan, the physician must be aware if the patient is pregnant or beast feeding. This medication carries a pregnant category of B and the drug can be excreted through breast milk. If pregnancy is expected or if it occurs, the physician should be consulted. It should only be used with caution in breast feeding or lactating women.

Medication should be taken 30 minutes prior to meals and taken as directed by the health care provider. It should be noted that the drug will become more effective over a time period of 2 to 4 weeks. Treatment should continue unless dictated otherwise by a physician. If a dose is missed or forgotten, the dose should taken as soon as possible. If the time for the next regular dose is near, the missed dose should be skipped. Never take more than one dose at a time. Doing so may result in an overdose. Drowsiness, irritability, disorientation, agitation, muscle hypertonia and extrapyramidal reactions are signs of overdose; if overdose is suspected seek the nearest emergency medical center or contact the poison control center.

Many people do not experience side effects when taking Reglan; however the side effects may include trouble sleeping, restlessness, headache, nausea and diarrhea. Drowsiness and dizziness are side effects and caution should be taken if driving or performing actions relying on motor skills.

In rare cases, there are can be more severe side effects which require the assistance of an emergency medical care facility. Any severe allergic reactions (hives, rash, difficulty breathing and swelling of mouth, face, throat, lips or tongue), abnormal thinking, dark urine, irregular heartbeat, seizures, persistent dizziness, shortness of breath, any involuntary movements of the eyes, face or limbs, changes in libido, mental or mood changes and stiff or rigid muscles are all severe side effects of Reglan.

This medication can interact with other medications, including cisapride or droperidol (may increase occurrence of muscle rigidity, increased heart rate or mental confusion), antihistamines, narcotic pain medicines, acetaminophen, levadopa, sedatives, monoamine oxidase inhibitors, cabergoline, digoxin and peroglide. The prescribing physician should not prescribe this medication without understanding the patient’s medical history and current drug list.

Reglan can interact poorly with several medical conditions. This medication can increase blood sugar levels in diabetes patients. Extreme caution should be taken when prescribing this drug to patients with Parkinson’s disease, the elderly, patients with hypertension, and women. Reglan can be a carcinogen to patients that previously diagnosed with breast cancer. Depression can occur in patients that have had previous issues with depression and in patients that never had a problem with depression. Nueroleptic malignant syndrome (NMS) is a possible fatal syndrome that can occur when taking this medication. Any signs of sweating, irregular heartbeat, confusion, abnormal thinking or muscle stiffness should report immediately to the prescribing physician.

Reglan has the following structural formula:

Chemical structure of reglan

• Molecular formula of reglan is C14H22ClN3O2
• Chemical IUPAC Name is 4-amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxy-benzamide
• Molecular weight is 299.796 g/mol
Reglan available : 5mg tablets, 10mg tablets

Generic name: Metoclopramide

Brand name(s): Cerucal, Clopra, Clopromate, Duraclamid, Elieten, Emetid, Emperal, Eucil, Gastrese, Gastrobid, Gastromax, Gastronerton, Gastrosil, Gastrotablinen, Gastrotem, Imperan, Maxeran, Maxolon, Meclopran, Metaclopramide, Metaclopromide, Metamide, Methochlopramide, Methoclopramide, Metochlopramide, Metoclol, Metoclopramida, Metoclopramidum, Metocobil, Metramid, Moriperan, Mygdalon, Neu-Sensamide, Octamide, Parmid, Paspertin, Peraprin, Plasil, Pramiel, Pramin, Primperan, Reclomide, Reliveran, Terperan

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