Reminyl review

Reminyl is a cholinesterase inhibitor used to treat the symptoms of mild to severe cases of Alzheimer’s disease. Its generic name is galantamine, an alkaloid originally derived from the bulbs of certain flowering plants such as daffodils. Reminyl works by increasing the acetylcholine content in the brain by preventing its breakdown. Acetylcholine makes the receptors in the brain more responsive, thus improving learning, memory and functioning of patients with Alzheimer’s. Recently, Reminyl has been renamed Razadyne and is available in extended release capsules, normal oral tablets and in liquid solution form.

Reminyl is usually taken in small quantities during the start of the treatment and is adjusted according to the patient’s response to the treatment. The initial dosage is about 8mg per day taken with or without food and is usually increased to 16mg per day after a minimum of 4 weeks. It may then be further increased to 24mg after another 4 weeks depending on the doctor’s assessment of your progress and tolerance. If taking the tablets or the liquid solution, Reminyl should be taken twice a day – once in the morning and another in the evening. The extended release capsule may be taken once a day during the morning. If you are taking the tablets and wish to switch to the extended release formula, you may do so by taking the extended release medication the next morning. Be careful not to crush or break the extended release capsule when taking it as it will prevent proper release of the medication in the body.

If treatment has been disrupted or discontinued for a few days, then administration of Reminyl should resume at the lowest dosage and slowly increased to your current dose.

Inform your doctor of any drug allergies or allergy to daffodil flowers, which may be triggered by Reminyl

If you have asthma or any lung disease, urinary tract blockage or stomach ulcers, take care when taking Reminyl as it may worsen your condition. Also, because Reminyl can cause the slowing of heart rate and possibly fainting, extra care should be taken if you have heart conditions.

Your dosage may need adjustment by your doctor if you have liver disease, as Reminyl is metabolized by the body through the liver.

While it may improve cognitive functions as a side effect of treatment for Alzheimer’s disease, Reminyl is not recommended to be used as treatment for memory disorders.

Reminyl may also interact with large doses of aspirin, other cholinesterase inhibitors, nonsteroidal anti-inflammatory drugs, cholinergic drugs and heart drugs such as calcium channel blockers. Consult your doctor if you take any of these medications.

It is common to experience nausea, vomiting, dizziness, weight loss, or appetite loss as a result of taking Reminyl. Gastrointestinal discomfort is also common. Others may experience less common side effects such as tremors, irregular heartbeat, indigestion or blood pressure changes. Consult your doctor if these effects persist.

If you experience chest pain or shortness of breath, consult your doctor immediately.

Reminyl has the following structural formula:

Chemical structure of reminyl

• Molecular formula of reminyl is C17H21NO3
• Chemical IUPAC Name is 4a,5,9,10,11,12-Hexahydro-3-methoxy-11- methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol
• Molecular weight is 287.354 g/mol

Generic name: Galantamine

Brand name(s): Galantamin, Galanthamine, Jilkon, Lycoremin, Lycoremine

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