is also generically prescribed as doxepin
and otherwise prescribed as Adapin
. Sinequan is commonly used to treat depression
as well as anxiety
which is typically associated with alcohol withdrawal
, manic depressive disorders, and serious psychiatric conditions. Sinequan is tricyclic antidepressants which affect the chemicals in the brain
that are believed to be off balance
in these conditions. It is vital that a patient who is beginning a tricyclic antidepressant is carefully monitored to avoid the development of suicidal thoughts or behaviors. While these behaviors can occur at any time during treatment, it is most prevalent during the initial 12 weeks of treatment.
A patient who has taken an MAO inhibitor anytime in the previous 14 days is likely to experience life threatening interactions when starting Sinequan. Tricyclic antidepressants and MAO inhibitors can not be missed, and ample time must be allotted to be sure one drug has cleared form the system before introducing the other medication.
Sinequan is not appropriate for everyone. It is vital that a thorough medical history is assessed previous to prescribing this medication. Patients with a medical history which includes either diabetes
or bipolar disorder
may not be able to take Sinequan or may require special monitoring procedures while undergoing drug therapy with this medication, depending on the severity of the condition.
The American Food and Drug Administration determined this medication may be harmful or cause birth defects on an unborn baby. It has yet to be determined whether or not this medication will pass through the mother’s breast
milk and cause harm to a nursing baby. This medication should not be prescribed to women who are pregnant or nursing, or to women with a high likelihood of becoming pregnant.
Like all medications, side effects may occur. Severe side effects require immediate emergency medical attention. Severe side effects may include an allergic reaction (swelling of the face, lips
, or throat, hive, and difficulty breathing), tremors
or uncontrollable shaking, lightheadedness, fainting, fast heart
rate, pounding heart, uneven heart rate, decrease in urination
, lack of urine output, seizures, confusion
, restless muscular movement of the jaw, neck, eyes, or tongue, unusual weakness, easy bruising, easy bleeding, or extreme thirst with nausea
, and weakness.
Less serious side effects are more typical and do not generally require emergency medical attention. The reporting of all side effects is likely to help the prescribing physician determine the correct dosage. It is likely that lowering the dosage of Sinequan may alleviate uncomfortable side effects. Less serious and more common side effects are likely to include symptoms such as dry mouth, swelling
of the breasts
in both genders, loss of appetite
, nausea, vomiting, constipation
, weakness, lack of coordination, changes in weight, numbness, tingling sensations, ringing in the ears, increased sweating, headache
, blurry vision, fatigue, drowsiness, dizziness
, nightmares, or impotence or other forms of sexual dysfunction.
It is very important that patients understand dosing instructions when taking Sinaquan, as an overdose can lead to serious health complications or death. Should an overdose occur, the patient should be directed or taken to the nearest emergency medical facility. Symptoms of and overdose may include agitation, excessive drowsiness, vomiting, uneven heart rate, blurry vision, feeling excessively hot or excessively cold, confusion, muscle stiffness, lightheadedness, fainting, hallucinations, seizures, coma, or death.
There are known drug interactions associated with Sinequan, and the prescribing physician should not only urge patients to inquire before taking any new medications, but should also assess a medical history complete with a current and recent drug list. Patients should inquire with the prescribing physician before taking over the counter medications, herbal remedies, and vitamin supplements. Medications with a known interaction with Sinequan include cimetidine
, and heart rhythm medication. Patients can not take an MAOI within 14 days of Sinequan and the can not take an SSRI within 5 weeks of Sinequan. This can lead to a deadly combination of medications.
Sinequan has the following structural formula:
• Molecular formula of sinequan is C19H21NO
• Molecular weight is 279.376 g/mol
• Sinequan available : 25mg capsules, 50mg capsules