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Sporanox

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Sporanox

Sporanox review





Sporanox can also be generically prescribed as itraconazole and is commonly used to treat three types of very serious fungal infections. Infections such as blastomycosis, which infects the lungs, bones, and skin, histoplasmosis, which affects the lungs, heart, and blood, and aspergillosis, which affects the lungs and kidneys and sometimes other various organs, are very serious conditions which require prompt and accurate treatment. Sporanox can also be used to fight fungal infections in patients with AIDS, which can be very serious due to the compromised immune system as well as used to fight fungal infections of the toe nails or finger nails. There is an oral solution of Sporanox that is used to treat fungal infections of the mouth, gums, tongue, throat, and esophagus.

Sporanox may make certain health conditions worse and should not be prescribed indiscriminately. Patients with a medical history which includes heart disease, congestive heart failure, and coronary artery disease, or cystic fibrosis with a low white blood cell count, as well as patients with additional infections such as a bacterial infection. Patients with liver disease can not take Sporanox.

The American Food and Drug Administration does not recommend prescribing Sporanox to patients who are pregnant, nursing, or who are likely to become pregnant. Sporanox has been proven to cause harm or birth defects in unborn babies as well as pass through the mother’s breast milk and affect a nursing infant.

There is a risk of serious side effects associated with Sporanox. Serious side effects and allergic reactions require immediate medical assistance. An allergic reaction is likely to present with symptom which include swelling of the lips, mouth, throat, or tongue, hives, and difficulty breathing. Other serious side effects are likely to include symptoms such as loss of appetite, sever fatigue, nausea, vomiting, dark urine, clay colored stools, jaundice, swelling of the feet or ankles, or difficulty breathing.

Other less serious side effects may occur, but typically do not require immediate medical care. Symptoms such as swelling from water retention, mild vomiting, anxiety, diarrhea, mild fatigue, gas, headache, high blood pressure, bursitis, fever, indigestion, muscle pain, inflammation of the sinuses, nausea, pain, rash, urinary infection, and respiratory infection.

Side effects associated with Sporanox oral solution include chest pain, cough, back pain, blood in the urine, difficulty swallowing, dehydration, difficulty breathing, weight loss, hemorrhoids, insomnia, pneumonia, inflammation of the mouth, hot flashes, vision problems, speech problems, shivering, and sweating.

Patients should be warned about the dangers of mixing medication without proper medical supervision. Alternatively, Sporanox should not be prescribed without a thorough medical history which includes a current list of medication and supplements. Medications that are known to cause serious and hazardous interactions include antacids, Xanax, Lipitor, BuSpar, blood thinners, calcium channel blockers, caffeine agents, busulfan, carbamazepine, cilostazol, clarithromycin, cyclosporine, diazepam, disopyramide, dofetilide, digoxin, docetaxel, eletriptan, erythromycin, indinavir, isoniazid, levacetylmethadol, lovastatin, methylprednisolone, midazolam, nevirapine, oral diabetes medications, phenobarbitol, phenytoin, pimozide, quinidine, rifabutin, rifampin, ritonavir, saquinavir, simvastatin, sirolimus, tacrolimus, triazolam, trimetrexate, and vinblastine.

Sporanox should be taken as it has been prescribed by the physician. In the event of a missed dose, the dose should be taken when remembered unless it is nearing time for the next scheduled dose. Patients should not double up on medication to make up for a missed dose and patients should never alter their own dosage to see faster results. An overdose may occur if taken improperly. In the even of an overdose the patient will require emergency medical care and may experience symptoms such as seizures, hallucinations, changes in behavior and a slow rate of breathing.

Sporanox has the following structural formula:

Chemical structure of sporanox


• Molecular formula of sporanox is C35H38Cl2N8O4
• Chemical IUPAC Name is 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl] methoxy]phenyl]piperazin-1-yl]phenyl]-2-(1-methylpropyl)-2,4-dihydro-1,2,4-triazol-3-one
• Molecular weight is 705.633 g/mol
Sporanox available : 100mg capsules, 10mg/ml solution

Generic name: Itraconazole

Brand name(s): Itraconazol, Itraconazolum, Itrizole, Oriconazole, Sporal, Sporanos, Sporonox, Triasporn

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