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Sumatriptan

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Sumatriptan

Sumatriptan review





Sumatriptan is the name of the medication that usually goes by the brand name Imitrex. It is prescribed for the treatment of migraines that have begun to take place, both with or without an aura. Sumatriptan usually comes in tablet form, but can also be given as an injection or a nasal spray.

Sumatriptan is only given for acute migraines, that is, migraines that are being experienced at the moment. It should not be taken as a preventative if you are not experiencing a migraine. But if you are experiencing migraine, it should be taken at the earliest possible indication that one is beginning. The earlier sumatriptan is taken, the more effective it is against the development of a migraine. If the headache returns, or if it only partially alleviates your symptoms, you can take a second sumatriptan pill after two hours, but you should not take more than two hundred milligrams in a day.

Some people should not take sumatriptan because of side effects and negative interactions with other drugs. If you take MAO-A inhibitors, that may cause the effects of sumatriptan to become unpredictable, so those two classes of medications should not be taken together. If you have liver disease, your absorption could be sped up, therefore you should take lower doses of sumatriptan. You should also not use sumatriptan with another class of migraine drugs called ergots within twenty-four hours of each other.

Sumatriptan is a very effective medication against migraines, but it can have serious side effects, as well. Some people taking sumpatriptan have had serious cardiac events, and some of these events have even been fatal. That side effect is very rare, but it should be noted that sumatriptan does affect the heart. Another rare side effect is elevated blood pressure. Other side effects include nausea or vomiting, chest pain or pressure, headache, dizziness, and sleepiness. People also sometimes experience runny nose, upper respiratory inflammation, and sensitivity to noise. Still others were diarrhea or constipation, sweating, tightness in the jaw or neck, and difficulty breathing. Again, even these side effects are rare, and sumatriptan has proven to be generally well tolerated by most people.

Sumatriptan has been known to cause birth defects when given to pregnant rats, but there are no studies done on human women. With such laboratory research, sumatriptan should not be given to pregnant women, unless the help given to the woman in alleviating her condition outweighs the risk to the fetus. In most cases where the patient is pregnant, other medications should be considered, even if they are not as effective. The effects of sumatriptan on children have also not been established, so sumatriptan should not be prescribed to children under eighteen. Likewise, sumatriptan is not recommended for the elderly, because they often have either decreased liver function or decreased heart function, both of which make sumatriptan risky to take.

Other people who should not take sumatriptan are people with high blood pressure, people who have had strokes or TIAs, people taking depression medications, or people who are experiencing a headache that is not a migraine.

Sumatriptan has the following structural formula:

Chemical structure of sumatriptan


• Molecular formula of sumatriptan is C14H21N3O2S
• Chemical IUPAC Name is 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide
• Molecular weight is 295.402 g/mol
Sumatriptan available : 6mg/0.5ml solution, 5mg/act solution nasal inhaler, 20mg/act solution nasal inhaler, 25mg tablets, 50mg tablets, 100mg tablets

Brand name(s): Imigran, Imitrex, Sumatran, Sumatriptanum, Sumax

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