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Tamoxifen

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Tamoxifen

Tamoxifen review





Breast cancer has become infamous for its ability to provide life-altering symptoms. It changes life in a snap that is why anti breast cancer drugs became in demand. In this light, Tamoxifen was born. ICI Pharmaceuticals, which now has the new company name AstraZeneca, discovered Tamoxifen and sold it under different brand names.

Tamoxifen became the world’s largest selling anti breast cancer drug in no time. It has been the most effective solution seen by many women, especially those in menopausal stage, as their best arm against the big C.

Tamoxifen is mainly used as a preventive medicine in women who are in high risk for contracting the disease. It is also used to reduce the risk of contralateral cancer. Tamoxifen is basically an anti-estrogen drug. It interferes in estrogen’s activity, which suppresses the growth of tumors that need estrogen to thrive.

Tamoxifen is also used to treat women infertility, gynecomastia, and bipolar disorder among others.

Before using Tamoxifen, it is important that you have discussed all factors that may affect the efficiency of the drug in your case. Some of the things that you need to tell your doctor about include allergies, previous medical conditions, and current drug intakes.

A high level of cholesterol in the blood is another major concern. Patients who have history of stroke, unusual and uncontrollable bleeding, high blood pressure, heart ailments, and diabetes are also given considerations. Your smoking habit must also be given attention to.

Pregnancy is also not recommended during and even after two months of your Tamoxifen treatment. Ask your doctor’s advice about a non-hormonal birth control method that you can use to ensure that you do not get pregnant and put your unborn child at harm’s way in the process. Tamoxifen is likewise not recommended to nursing mothers. You need to stop breastfeeding your child once you start taking Tamoxifen.

Tamoxifen comes in tablet form. It is usually prescribed one to two times a day. To improve your chances of benefiting from the drug, make sure that you do not miss out on your dose. Take your medicine at about the same time each day to eliminate the possibility of missing out on a dose.

Tamoxifen as a preventive, anti-breast cancer drug is usually prescribed for five years of continued use. For breast cancer treatment, it is usually the doctor’s the decision for how long it will be used. Importantly, you need to work closely with your doctor. Never stop taking Tamoxifen or adjusting its dosage without consulting your doctor first.

If Tamoxifen promises freedom from breast cancer, it also poses some alarming risks. One of the many side effects of the drug is the possibility of developing cancer of the uterus. This is but one of the many reasons you should keep an eye on your symptoms once you start treatment. If you experience bloody vaginal discharge, irregular menstrual periods, chest pain, and vision changes among others, rush to see your doctor. If you are to use Tamoxifen as a preventive drug against breast cancer, discuss all factors with your doctor including the benefits and risks of undergoing this medication therapy.

Tamoxifen has the following structural formula:

Chemical structure of tamoxifen


• Molecular formula of tamoxifen is C26H29NO
• Chemical IUPAC Name is 2-[4-(1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethyl-ethanamine
• Molecular weight is 371.515 g/mol
Tamoxifen available : 10mg tablets, 20mg tablets

Brand name(s): Apo-Tamox, Citofen, Crisafeno, Diemon, Gen-Tamoxifen, Istubol, Kessar, Noltam, Nolvadex, Nolvadex-D, Nourytam, Novo-Tamoxifen, Oncomox, Pms-Tamoxifen, Retaxim, Tamizam, Tamofen, Tamone, Tamoxasta, Tamoxen, Tamoxifene, Tamoxifeno, Tamoxifenum, Trans-Tamoxifen, Valodex, Zemide

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