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Tavist

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Tavist

Tavist review





Tavist is an antihistamine medication having sedative and anticholinergic effects that can quickly reduce allergy symptoms within 24 hours. Though there are a number of precautions and side effects to watch out for. It is used to treat allergy symptoms including runny nose, swelling, itchy skin, hives, rash, sneezing, red and teary eyes and pruritus. It is also known as Meclastin and is classified as an antipruritic. Tavist is able to increase capillary dilatation and permeability as well as improve gastrointestinal and respiratory smooth muscle contraction.

Tavist may cause paradoxical effects like CNS depression and stimulation. By blocking the effects of natural-occurring histamine, it inhibits histamine's vasodilator and vasoconstrictor effects. The medication comes in pills and extended-release pills, which should be taken orally. It is also available as a syrup.

Tavist can cause some side effects including drowsiness, dry mouth, nose or throat, dizziness, chest congestion, cephalalgia, upset stomach, excitability, nervousness, pupil dilation, extra sunlight sensitivity, heart palpitation, sleepiness, enlarged prostate and difficulty urinating. These should be reported to your physician, particularly if they become severe. Other reactions include loss of appetite, vision changes and irritability. Some symptoms are mild and will only be present as the body adjusts to the medication. Serious side effects like breathing difficulty, irregular heartbeat and ear ringing should be reported to your physician immediately.

Patients with hypersensitivity reactions to the medication should never take it. Those with a history of lung disease, asthma, glaucoma, ulcers, difficulty urinating, enlarged prostate, overactive thyroid, hypertension, seizure and heart disease should consult their physician before taking this medication. Breastfeeding mothers and pregnant women should also talk with their physicians before taking this medication. And elderly patients may require lower dosages since they are more sensitive to the medication. Tavist may interact negatively with medications including MAOIs or monoamine oxidase inihibitors, sedatives, tranquilizers, narcotics and antipsychotics.

Tavist acts by aggressively binding to H1-receptor sites which makes it a selective histamine H1 antagonist. The sites are then blocked, preventing endogenous histamine from attaching. When endogenous histamine is blocked, it cannot cause symptoms and reactions, so the patient experiences temporary relief. The medication is thought to be metabolized in the liver by mono-didemethylation and glucuronide conjugation.

In a study, 12 patients suffering from anaphylactic reactions were given 1 mg of Tavist 4 times a day for 3 days. Within the first 24 hours, all participants had reduced symptoms and were completely free of symptoms by the second day. The only drawback was that 10 of the participants reported sleepiness that lasted up to 1 week after treatment was over.

Tavist is an over-the-counter medication so a prescription is not needed. It is available in almost all pharmacies and drug stores. Check the expiration date and manufacturer to ensure quality and freshness of the medication. The medication may also be ordered online at certified pharmacies.

Drowsiness is one of the most common side effects of Tavist so patients should not drive or operate heavy machinery until full effects are realized. Children younger than 12 years old should ask a physician first to ensure safety. The medication should be stored at room temperature away from sunlight and moisture. Dosage should also be followed religiously and patients should never take more or less than recommended.

Tavist has the following structural formula:

Chemical structure of tavist


• Molecular formula of tavist is C21H26ClNO
• Chemical IUPAC Name is 2-[2-[1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]-1-methyl-pyrrolidine
• Molecular weight is 343.89 g/mol
Tavist available : 1mg tablets

Generic name: Clemastine

Brand name(s): Clemastina, Clemastinum, Meclastin, Mecloprodin, Tavegil

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