Ticlopidine review

The main use of Ticlopidine is to prevent blood clotting. It is also used to reduce the chances of stroke, and can be used in combination with aspirin in certain types of procedures—for example, coronary stent implantation—without any dire consequences. This medicine must be used only when aspirin is ineffective or if a patient is allergic to aspirin.

The most suitable dose of Ticlopidine for people with stroke is 250 milligrams two times a day taken with food. Other possible doses have not been examined in controlled trials for this medication. As for coronary artery stenting, the recommended dose is 250 milligrams two times a day taken with food and anti-platelet doses of aspirin for up to a month or thirty days of therapy after successful stent implantation.

Inform your healthcare professional of your medical history, particularly of the following conditions: ulcers; low blood cell counts disease like anemia, neutropenia, thrombocytepenia, and TTP; allergies; kidney disease; high blood cholesterol; high blood fats or triglycerides; liver problems; and blood disorders. For pregnant mothers, the medicine isn't outright forbidden for them to take, but it should only be taken when clearly needed.

You should also tell your pharmacist or doctor if you are allergic to ticlopidine or any other medicine. Certain prescription and nonprescription drugs can harmfully interact with this medication, particularly anticoagulants or blood thinners, aspirin, antacids, theophylline, cimetidine, digoxin, and certain vitamins. If you really need to take antacids, then do so one or two hours after taking ticlopidine to avoid any dangerous side effects.

Moreover, it may take longer for bleeding to stop while taking this drug because, as already mentioned, it is specifically designed to prevent blood clotting. It is prudent to notify your doctor about any unusual bruising or bleeding as soon as you possibly can.

In addition, you must report to your dentist or any doctors and surgeons that you are using this drug. You also have to go through a series of laboratory or medical tests in order to properly observe any dire side effects and to check your present blood count. Furthermore, you shouldn't share this medication with other people; this type of drug can only be prescribed.

Finally, notify your doctor about the risks and benefits of ticlopidine treatment during pregnancy. It is unknown if this medication passes into breast milk, so breastfeeding is not recommended while using this drug. For all other questions and concerns, consult your doctor.

During the first few days of treatment, expect your body to experience stomach pain, headache, diarrhea, stomach upset, vomiting, dizziness, nausea, flatulence, itching, and loss of appetite. Your body should adjust to the medication after that period, but if these effects persist or worsen, consult your doctor immediately. You should also inform your doctor as soon as the following side effects occur: critical or continuous diarrhea, light-colored stool, mental or mood changes, and skin rash.

Very rarely, ticlopidine also causes speech problems, seizures, fever, weakness, yellowing of the eyes or skin, pale skin, pinpoint bruises, and dark urine. These side effects are much uncommon than the ones already mentioned, but they are even more dangerous, so consult your doctor immediately. Most of all, this drug can affect your blood cell count, so you'll probably be more prone to infection. If you have symptoms of infection like fever, chills, and sore throat, consult your doctor.

Ticlopidine has the following structural formula:

Chemical structure of ticlopidine

• Molecular formula of ticlopidine is C14H14ClNS
• Chemical IUPAC Name is 3-[(2-chlorophenyl)methyl]-7-thia-3-azabicyclo[4.3.0]nona-8,10-diene
• Molecular weight is 263.786 g/mol
Ticlopidine available : 250mg tablet

Brand name(s): Ticlid

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