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Tolterodine

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Tolterodine

Tolterodine review





Tolterodine is a drug used mostly to relieve urinary sicknesses, including excessive urination and urinary incontinence. It is under a class of drugs called anti-muscarinics, and it works by preventing the bladder from contracting.

Although it acts on all types of receptors, tolterodine has fewer side effects than other anti-muscarinics because it efficiently targets the bladder more than the other areas of the body. This means that less of the drug needs to be given daily in order to achieve maximum therapeutic effect, so there are fewer side effects.

Tolterodine comes in two forms: tablet form and extended release or long-acting capsule form, both of which are taken orally. Take this drug in the mouth exactly as prescribed by your doctor. The tablet form is typically taken twice a day, while the extended release capsule is usually taken once a day with liquids.

Follow the directions on your prescription label carefully, and don't hesitate to ask your pharmacist or doctor to explain any part of the directions that needs clarification. Both forms of the medication can be taken with or without food and must be swallowed whole. Do not crush or chew either form of the drug.

Don't forget to inform your healthcare specialist of your medical history, including any allergies you may have, narrow-angle glaucoma, stomach or intestinal disorders like gastric retention or pyloric stenosis, kidney problems, liver problems, difficulty with urination, urinary retention, or prostate enlargement.

Observe caution when performing tasks that require mental alertness—that is, driving or operating heavy machinery—while under treatment, because this medication has been known to affect awareness and concentration.

If you miss taking a dose of tolterodine, do not double up your dosage. Instead, just take it as soon as you can remember. Moreover, if you remember missing the dose near the time of the next dose, skip the missed dose and resume your regular dosing schedule instead of taking the missed dose anyway. Trying to catch up could possibly lead to overdose.

This medication has been known to reduce sweating, which can lead to heatstroke in hot weather. As such, consult your doctor or pharmacist if you live or work in a hot environment where the possibility of heatstroke is imminent. The elderly must be cautious when taking this drug because they might be more sensitive to its side effects should they occur.

Tolterodine should only be used when clearly needed during pregnancy. Discuss the pros and cons of using this medication while pregnant to your doctor. It is currently not known whether this drug passes into breast milk, although the risk is clearly there. Therefore, breastfeeding while using this medication is obviously not recommended. Again, consult with your doctor the safety of using tolterodine if you are presently breastfeeding.

Side effects when taking tolterodine include dry eyes, constipation, dizziness, nausea, headache, drowsiness, urinary burning, frequent urination, vision problems, eye pain, severe stomach pain, chest pain, fast heartbeat, hot or dry skin, and mood swings. If symptoms continue or become more severe after the first few days of treatment, consult your doctor as soon as possible. To relieve dry mouth, chew sugarless gum, suck on sugarless hard candy or ice chips, use a saliva substitute, or drink water.

Tolterodine has the following structural formula:

Chemical structure of tolterodine


• Molecular formula of tolterodine is C22H31NO
• Chemical IUPAC Name is 2-[3-[bis(1-methylethyl)amino]-1-phenyl-propyl]-4-methyl-phenol
• Molecular weight is 325.488 g/mol
Tolterodine available : 1mg tablets and 2mg tablets

Brand name(s): Detrol, Detrol LA, Tolterodina, Tolterodinum

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