is a benzodiazepine medicament with anxiolytic, sedative, and anticonvulsant properties. It affects the chemicals in the patient's brain
which, when unbalanced, can result in seizures or anxiety
Tranxene is recommended for patients needing relief from anxiety, seizures, and agitation resulting from alcohol withdrawal
. It can also be used for irritable bowel syndrome
. This medicament is also available under the brand names Novo-Clopate.
Tranxene is available in tablet form and is taken orally. It can be taken up to four times a day, with a minimum dose of 15 milligrams and maximum of 60 milligrams. It can be taken on an empty stomach
The medicament will begin to act on the body a couple of hours after taking it. The effects can be felt for one day or longer in some cases.
Since Tranxene is habit-forming, patients are advised not to take larger doses or use it for a longer period than prescribed by their doctor. Patients may develop tolerance with the medicament if it is used improperly, resulting in the medicament becoming less effective.
Patients should not skip a dose. Follow the regular dosing schedule as prescribed by the doctor. Patients should not take Tranxene for longer than 4 months without consulting their doctor. Suddenly stopping use of the medicament can worsen the patient's condition and result in various withdrawal symptoms including irritability, anxiety attacks, and sleeplessness.
Patients should never take a double dose to make up for a missed dose. In the event of a missed dose, simply take it as soon as remembered. If the next dose is almost due, skip the missed dose and take Tranxene as scheduled.
Patients taking Tranxene may also experience side effects, although the chances are quite low. Some common side effects may include drowsiness, tiredness, dizziness
, xerostomia, weakness, upset stomach, diarrhea
, and changes in mood and appetite.
Some more serious side effects include restlessness, severey in or frequent urination
, blurred vision, changes in libido, seizures, fever
, shuffling walk, persistent tremor, skin rashes, irregular heartbeat
, and severey in swallowing
Before taking Tranxene, patients should tell their doctor of any allergy
to any of these medicaments: alprazolam
, chlodiazepoxide, flurazepam
, prazepam, oxazepam, temazepam, and triazolam. These medicaments may interact negatively with Tranxene.
Non prescription and prescription medicaments including antihistamines, digoxin
, disulfiram, isoniazid, fluoxetine
can also affect the effectiveness of Tranxene.
Tranxene can also be less effective when taken along with medicaments for seizures, depression
, pain, Parkinson's disease, asthma
, and allergies
, as well as medicaments such as muscle relaxants, probenecid, oral contraceptives, rifampin
, sedatives, and sleeping pills.
Patients should also disclose to their doctor their medical history especially if they have had seizures, glaucoma
, and heart
illnesses. Women who are pregnant or are planning to conceive should also talk with their doctor before agreeing to take Tranxene.
Tranxene has the following structural formula:
Molecular formula of tranxene is C16H11ClN2O3
Chemical IUPAC Name is 7-chloro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylic acid
Molecular weight is 314.7231 g/mol
Tranxene available : 20mg tablets