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Trazodone

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Trazodone

Trazodone review





Trazodone is primarily used to treat depression, although it may also be used for other off-label purposes. This medication is a versatile psychoactive drug that can act as a sedative, anxiolytic, and antidepressant. The various manufacturers of this compound claim that its antidepressant properties activate during the first week of treatment.

Trazodone also has less prominent side effects of an anticholinergic (constipation, dry mouth, and tachycardia) and adrenolytic (male sexual problems, hypotension) nature compared to other trycyclic antidepressants.

The typical starting dose is 150 to 200 milligrams daily in 2 or 3 divided doses with food, and may be increased according to the tolerance or response of the patient by increments of 50 milligrams. In some individuals, doses may go up to 400 milligrams daily, although there have been hospitalized patients who take 600 milligrams daily as well.

Take this medication exactly as directed by your pharmacist or doctor. You should not take it in larger amounts or take it longer than prescribed. Follow the directions found on your prescription label, and clarify any part of it that you do not understand with your doctor or pharmacist. Your doctor may adjust your dose to make sure you'll get the optimum effects of the drug. Trazodone is most effective after you take it with a snack or a meal.

Consult your doctor of pharmacist first if you are allergic to any drugs including this drug or if you have schizophrenia, manic depression or bipolar disorder, any other psychiatric illness, suicidal thoughts, a history of drug abuse, or if you have recently had a heart attack before taking this medication. If you have any of the abovementioned conditions, you may need to adjust your trazodone dosage or take special tests to safely take the drug.

It's been documented that people who first start taking antidepressants have a tendency to develop suicidal thoughts, especially if they are younger than 24 years old. As such, you doctor, your pharmacist, or a psychiatric expert will need to check your current state of mind via frequent visits for at least the first 12 weeks of therapy.

As noted in the section below, trazodone can cause side effects that may impair your judgment or reactions, like drowsiness and loss of alertness. If you are taking this medication, be careful when driving, handling heavy machinery, or doing anything that requires attentiveness and concentration.

Stop taking this drug and contact your doctor promptly if you have an erection that lasts for four hours or is painful. This is a sign of a medical emergency that could lead to a serious condition that must be corrected with surgery. You also need to get emergency medical assistance if you get any of the symptoms of an allergic reaction: difficulty in breathing, the swelling of your lips, tongue, face, or throat, and hives.

Contact your doctor as quickly as you can if you develop any new or worsening symptoms, like anxiety attacks, panic attacks, sleeping troubles, mood or behavior changes, sudden impulsiveness, agitation, aggressiveness, hostility, restlessness, hyperactivity, worsening depression, or thoughts of committing suicide or hurting yourself.

Trazodone has the following structural formula:

Chemical structure of trazodone


• Molecular formula of trazodone is C19H22ClN5O
• Chemical IUPAC Name is 8-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-6,8,9-triazabicyclo[4.3.0]nona-2,4,9-trien-7-one
• Molecular weight is 371.864 g/mol
Trazodone available : 50mg tablets, 100mg tablets, 150mg tablets and 300mg tablets

Brand name(s): Beneficat, Bimaran, Desirel, Desyrel, Molipaxin, Pragmazone, Sideril, Thombran, Tombran, Trazalon, Trazodil, Trazodon, Trazodona, Trazodonum, Trazolan, Trazonil, Trialodine, Trittico

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