Tretinoin review

An acid form of Vitamin A also known as all-trans retinoic acid (ATRA) tretinoin is commonly used to treat keratosis pilaris and acne vulgaris. This medicine is known to improve the appearance of the skin by reducing roughness, improving coloration, and eliminating fine lines and wrinkles. It can also be used to treat milder conditions of acne that are not as severe as acne vulgaris.

Tretinoin which comes in either gel or cream form is mostly used on the face as directed on the label, usually once a day before bedtime. The directions for use are as follows: First, clean your face and wipe it dry. Second, apply a pea-sized amount of cream while using just enough to cover your entire face lightly. Be careful to avoid your nostrils, mouth, and eyes when applying the product. Third, wash and rinse and then wash your hands after use. Do not use in large amounts or more often than directed.

Excessive use will not give you better or faster results; instead, it will only increase the risk of side effects or other complications. Moreover, do not use this product on eczema, sunburn, and most other serious skin conditions that it isn't supposed to treat, because it might just aggravate them. The results from this medication are gradual, with the first signs of improvement only noticeable within the first six months of continued treatment. If used for acne, there's a possibility that the condition might worsen at first before improving.

If you have pre-existing skin disorders, allergies, and whatnot, it's important to inform your doctor or pharmacist about them before beginning tretinoin treatment. If you are prone to sunburn, then you probably should not be using this product in the first place, because it actually increases your skin's sensitivity to the sun. If you choose to continue taking this medication regardless, then it would be prudent for you to limit your sun exposure and avoid sun lamps. Also wear protective clothing and use sunscreen when outdoors.

If you're an expecting mother, then this medication should only be used when needed. You should also discuss with your doctor the advantages and disadvantages of undergoing tretinoin treatment if you're pregnant or planning to be pregnant. It is currently not known if tretinoin passes into breast milk, so further medical consultation is advised before breastfeeding while under treatment.

Inform your doctor or pharmacist of any prescription or nonprescription medicine you may be currently taking or have taken in the past, including amiodarone, isotretinoin, tetracyclines or guinolone antibiotics, sulfa-drugs, or phenothiazines, because they all increase your skin's sensitivity to the sun, and a double dose of any of those drugs and tretinoin can cause grave, sunlight-related problems to your skin.

Using tretinoin can cause scaling, stinging, itching, burning, peeling, and drying of the skin for the first several weeks as your body adjusts to it. If any of those side effects persist or worsen, discontinue use of the product and consult your doctor promptly. If you begin to experience crusting, swelling, or blistering of the skin and the darkening or lightening of your skin color, then contact your doctor or pharmacist as soon as possible in order have these serious symptoms treated.

Tretinoin has the following structural formula:

Chemical structure of tretinoin

• Molecular formula of tretinoin is C20H28O2
• Chemical IUPAC Name is 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-nona-2,4,6,8-tetraenoic acid
• Molecular weight is 300.435 g/mol
Tretinoin available : 0.05% cream or gel

Generic name: Alitretinoin

Brand name(s): Avita, Beta-retinoic acid, Panretin, Panretyn, Panrexin, Renova, Retin-A, Retinoate, Retinoic acid, Trans-Retinoic acid, Vesanoid, Vitamin A acid

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