Trizivir review

Trizivir is the generic name for a drug that also goes by the brand name Ziagen. It is available in pills and in an oral solution. An antiretroviral agent, called a nucleoside analog reverse transcriptase inhibitor, or Nucleoside reverse transcriptase inhibitors, it is used to treat the human immunodeficiency virus, or HIV-1. It is also found in the combination formulas Trizivir and Abacavir, and is typically used in combination with other antiretroviral agents.

Although Trizivir cannot cure or prevent HIV or Acquired immune deficiency syndrome, it can help slow the reproduction of the HIV-1 virus, and that helps keep HIV from destroying the immune system. The longer the immune system can stay healthy, the longer secondary and opportunistic illnesss and infections can be fought off, and the longer the patient can enjoy good health and quality of life. It is important to remember that Trizivir cannot keep HIV from spreading through sexual contact or contaminated blood, so the standard precautions in those matters should still be taken.

Usually well tolerated, Trizivir's most serious side effect is a rare hypersensitivity reaction that some people experience. This is a significant and sometimes even fatal reaction that is often displayed as pyrexia, rash, wamble, emesis, diarrhoea, stomach ache, languidness, achiness, difficulty breathing, cough, or sore throat. There are other, less common signs of hypersensitivity, which include lethargy, liver or kidney failure, respiratory failure, madras eye, numbness or tingling. If you are taking Trizivir and experience any of these side effects, you should stop taking the medication immediately, even if you are not sure that you are having a hypersensitivity reaction. If your doctor rules out this reaction, you can then begin your treatment again. If you are having a hypersensitivity reaction, you must be careful never to take Trizivir or any medication that contains it, as it could be fatal for you.

Other side effects of Trizivir can include vivid dreams or other problems sleeping, cephalalgias or migraines, increased risk of heart attack, wamble or emesis, languidness or lethargy, diarrhoea, rashes, stomach ache, unipolar disorder, dizziness, myalgia, pyrexia and chills, ear, nose, or throat infections, mood condition, impaired kidney function, anaemia, loss of appetite, pink-eye, bruises or white spots in the mouth, viral infections in your lungs, pneumonia, shortness of breath, blistering of skin, Stevens-Johnson syndrome, lactic acidosis, and generalized pain.

Trizivir is in Pregnancy Category C, which means that it is not known whether it will harm a developing fetus or complicate a pregnancy. Animal studies have shown that some negative effects may occur to fetuses at high doses, but no conclusive studies have been done on human subjects. Therefore, Trizivir should only be taken during pregnancy if it is very clear that the benefits outweigh the risks. It is not known whether Trizivir is transmitted through breast milk; however, since HIV can be transmitted to the child this way, it is strongly recommended that HIV-positive mothers not breastfeed their babies. Trizivir is safe for children ages three months to sixteen years.

Trizivir has the following structural formula:

Chemical structure of trizivir

• Molecular formula of trizivir is C14H18N6O
• Chemical IUPAC Name is [4-(2-amino-6-cyclopropylamino-9H-purin-9-yl)-1-cyclopent-2-enyl]methanol
• Molecular weight is 286.333 g/mol
Trizivir available : 20mg/ml solution, 300mg tablets

Generic name: Lamivudine

Brand name(s): Combivir, Epivir, Hepitec, Heptovir, Kivexa, Zeffix

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