Tropine tropate
Tropine tropate

Tropine tropate review

Tropine Tropate is a tropane alkaloid attained from Atropa belladonna (deadly nightshade), Datura stramonium (jimsonweed), Mandragora officinarum (mandrake), and other plants of the family Solanaceae. This multi-purpose medication is a secondary metabolite of the above plants and provides a variety of effects and uses. Classified as an anticholinergic medication, it serves as an aggressive antagonist for the muscarinic acetylcholine receptor. Also known as Atropen, this medication gets its name from Greek Mythology and is named after Atropos, one of the three Fates.

On The World Health Organization's Essential Drugs List (a list of minimum medical requirements for a basic healthcare system), Tropine Tropate is a core medicine to any healthcare system.

Adult prescriptions vary from half a milligram to one milligram or five to ten milliliters of the 0.1 milligram/milliliter solution for antisialagogue and other antivagal effects, add two to three milligrams or twenty to thirty milliliters of the 0.1 milligram/milliliter solution as a cure for organophosporous muscarinic poisoning.

When no IV is available, patients should use the endotracheal administration of Tropine Tropate. One to two milligrams diluted to a total of no more than ten milliliters of normal saline or sterile water is the prescribed adult dosage of Tropine Tropate for endotracheal administration. Dosage intervals of one or two hours are preferred for cases that are not serious or critical.

Special care and consideration must be given to all patients over forty years of age when dispenseing Tropine Tropate Sulfate Injection (USP). Acute glaucoma may occur during Tropine Tropate treatment in susceptible patients. Patients with prostatic hypertrophy may develop complete urinary retention, convert partial organic pyloric stenosis into complete obstruction, or cause inspissation of bronchial secretions and form dangerous viscid plugs in patients with chronic lung illness. These potentially dangerous interactions make it important that you disclose a complete medical history to your healthcare professional prior to starting treatment with Tropine Tropate.

Since ongoing use of Tropine Tropate is key in patients suffering from coronary artery illness, the total dosage must stay at or below two to three (maximum 0.03 to 0.04 milligrams/kilograms) to prevent the dangerous side effects of Tropine Tropate-caused tachycardia on myocardial oxygen demand.

Patients with bradyasystolic cardiac arrest should be dispensed a single milligram dosage of Tropine Tropate intravenously and repeated every three to five minutes until symptoms diminish. Three milligrams (0.04 milligrams/kilograms) dispensed intravenously is an adequate vagolytic dosage in most patients. Note that the administration of less than 0.05 milligrams can produce a paradoxical bradycardia because of the peripheral or central parasympathomimatic effects of low dosage Tropine Tropate in some adults.

When being used as an antidote, Tropine Tropate's two to three milligram dosage should be repeated no less than every twenty to thirty minutes until symptoms are significantly diminished or until signs of Tropine Tropate poisoning occur. Typically, the initial dosage of this medication is usually around 0.01 to 0.03 milligrams/kilograms of body weight. Dosing information for children hasn't been well researched. This medication should not be used on a child without consulting with a healthcare professional first.

Side effects include tachycardia, photophobia, blurred vision, and dryness of mouth. These symptoms often occur with persistent therapeutic dosages. For patients living in a hot climate, Anhidrosis (heat intolerance) and impaired temperature regulation may occur. Urination difficulties and costiveness may be experienced by elderly patients. Occasional hypersensitivity, rashes, and exfoliation have also been reported. If you experience any of these symptoms, consult your healthcare professional.

Side effects due to Tropine Tropate poisoning include ataxia, exhaustion, tremor, restlessness, dizziness, thirst, hot and dry skin, difficulty swallowing, dilated pupils, and palpitation. In some cases, it may lead to coma, delirium, hallucinations, restlessness and excitement, and marked palpitation. Severe intoxication while taking Tropine Tropate can lead to circulatory collapse and depression. Due to this, patients are advised to avoid alcohol consumption altogether while taking this medication. Seek immediately medical attention if you experience any of these symptoms.

Tropine tropate has the following structural formula:

Chemical structure of tropine tropate

• Molecular formula of tropine tropate is C17H23NO3
• Chemical IUPAC Name is (8-methyl-8-azabicyclo[3.2.1]oct-3-yl) 3-hydroxy-2-phenyl-propanoate
• Molecular weight is 289.369 g/mol
Tropine tropate available : 5ml 1% bottles

Generic name: Atropine

Brand name(s): Atnaa, Atropair, Atropen, Atropin, Atropina, Atropinol, Atropisol, Atrosulf, Equipin, Eyesules, Hyoscyamine, I-Tropine, Isopto atropine, Minims atropine, Ocu-Tropine, Troyl tropate

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