Valdecoxib review

Valdecoxib is an NSAID or nonsteroidal anti-inflammatory drug that is used to relieve inflammation, pain, and swelling. It is mainly used to treat conditions involving arthritis, including rheumatoid arthritis or osteoarthritis. As already mentioned, it is classified as an NSAID, so it shouldn't be taken by anyone who is allergic to these types of drugs.

Valdecoxib usually goes by the brand name of Bextra, and its commercial form was approved the FDA on November 20, 2001. It has been available by prescription in tablet form until 2005, when it was recalled and removed from the market due to concerns about possible increased chances of stroke and heart attack when using it.

The usual recommended valdecoxib dose for either rheumatoid arthritis or osteoarthritis is ten milligrams taken once daily. As for the treatment of primary dysmenorrhea, the advised dose is twenty milligrams twice daily as needed. Furthermore, this drug may be taken with or without food.

Before taking this drug, you should inform your pharmacist or doctor if you're allergic to it or to sulfa drugs; other NSAIDs like aspirin, celecoxib, valdecoxib, or ibuprofen; or have any other allergies in general. It is also not advised for you to use this medication if you suffer from medical conditions like severe liver disease or kidney disease.

Grave allergic reactions have been reported with valdecoxib, so it is recommended to patients who experience rash during initial treatment to discontinue using the drug and seek immediate medical advice from their physician. Although valdecoxib is not a sulfonamide in and of itself (in contrast to celecoxib), it is still discouraged for patients with an allergy to sulfonamides to take this drug.

Inform your doctor of you medical history as well, especially if you have suffered or are currently suffering from asthma, liver problems, stomach problems involving internal bleeding and ulcers, heart disease, swelling problems due to fluid retention, blood disorders like anemia, conditions caused by persistent tobacco or alcohol use, high blood pressure, poorly controlled diabetes, dehydration, nasal polyps, and persistent runny nose.

This drug should only be used when clearly needed during pregnancy, but should not be used altogether if the pregnancy is already in its third trimester. It is also unknown whether or not this medicine passes into breast milk. Therefore, in order to avoid potential risk to the unborn child, breastfeeding while using this drug is not advised.

Drugs related to valdecoxib rarely have caused blood cots to form, resulting in strokes and heart attacks. In addition, this drug has also rarely caused similar problems in heart bypass patients after surgery, but not in other people examined to date. As such, consult with your pharmacist or doctor about the pros and cons of veldecoxib treatment, as well as other possible drug alternatives.

The most typical side effects for this drug include headache, nausea, diarrhea, flatulence, insomnia, abdominal pain, and stomach bleeding. Other less common side effects include weakness, drowsiness, flu-like symptoms, fluid retention, weight gain, photosensitivity, anxiety, blurred vision, bleeding, stomach and intestinal ulcers, deafness, ringing in the ears, chest pain, worsening of pre-existing hypertension, heart failure, kidney failure, and fainting.

Valdecoxib has the following structural formula:

Chemical structure of valdecoxib

• Molecular formula of valdecoxib is C16H14N2O3S
• Chemical IUPAC Name is 4-(5-methyl-3-phenyl-oxazol-4-yl)benzenesulfonamide
• Molecular weight is 314.36 g/mol
Valdecoxib available : 10mg tablets and 20mg tablets

Brand name(s): Bextra

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