Psychiatric conditions such as epilepsy
and bipolar disorder
find relief in a drug called Valproate
. This is an anticonvulsant drug that controls the severity and the frequency of attack by reducing electrical activity in the brain
Valproate seeks to preserve the quality of life that even those affected by psychiatric disorders deserve. Although this drug is prescribed to treat different types of mania, it is more commonly known as part of an antiepileptic treatment.
Valproate must be used with caution. Before prescription, all the factors that may affect the use of the drug must be fully established. Discuss your allergies
, current drug intake, medical history, and the like with your doctor. He will determine from there if indeed you are fit to use the drug.
Valproate is not advisable to be used in pregnant women. Several studies show that the drug can pose fetal harm due to its strength and its use along with other strong drugs. Discuss your options with your doctor if you are pregnant to ensure that both you and your baby are safe. Valproate has been related to cases of autism, facial abnormalities, dyslexia, and vision defects in children whose mother went under treatment during pregnancy. As such, it is recommended that other, weaker alternatives be used instead.
Valproate comes in different forms and formulations – liquid suspension, tablet, and injection. It must be taken regularly as directed by the physician and with food. Never take Valproate with an empty stomach
. It may result to discomforts afterwards.
The dosage and treatment duration for a patient nominated for a Valproate therapy depends on a lot of factors and is on a case-to-case basis. No patient may use another person’s prescription even when they have similar symptoms. You must consult a doctor to obtain your own prescription.
Normally, Valproate is started in a low dosage that is increased until the ideal dose is reached. The ideal dose is a point when the condition is controlled with the treatment. For the entire duration of your Valproate therapy, you must be kept under close monitoring to ensure that your body is working well with it. Clinical and laboratory tests every once in a while are also undertaken to check of any unwanted side effects.
Valproate has been associated with common, mild side effects including diarrhea
, increased appetite, weight gin, drowsiness, stomach cramps, nausea
, and vomiting
. Such symptoms usually occur since your body is not yet adjusted to the drugs. Once you get used to having the drug in your system all of your side effects are expected to disappear. If you experience persistence or worsening of such symptoms, tell your doctor. It is also advisable that you consult your doctor once you observe the signs of more serious and severe side effects. Breast
enlargement, milk discharge, hair loss
, double vision, allergic reactions
, and unusual bleeding are some of the signs you must look through. If you experience any of those, you must rush to your doctor immediately so your symptoms are controlled.
Valproate has the following structural formula:
• Molecular formula of valproate is C16H31NaO4
• Chemical IUPAC Name is sodium; 2-propylpentanoate; 2-propylpentanoic acid
• Molecular weight is 310.405 g/mol
• Valproate available : 250mg tablets and 500mg tablets