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Valproic acid

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Valproic acid

Valproic acid review





A chemical compound that has found medical use as an anticonvulsant and mood-stabilizing drug, Valproic acid is mainly used in the treatment of bipolar disorder or manic depression, epilepsy, and less commonly major depression. It can also be used for migraine headache treatment and schizophrenia therapy. Related drugs include the sodium salts combined formulation valproate semisodium, which is used as a mood stabilizer and an anticonvulsant in the U.S., and sodium valproate, which is used exclusively as an anticonvulsant.

Take this medication orally as instructed by your physician. The recommended dose for this drug in tablet form is 500-1000 milligrams given once a day. For migraines, it's 250 milligrams twice a day, and for bipolar disorder, it's 750 milligrams per day. You may take it with food if you suddenly get an upset stomach. For more dosage information, consult your doctor.

Do not crush or chew the drug because it can irritate your throat or mouth. Instead, swallow the medication whole. Your dosage is based on your medical condition, weight, and response to therapy. In addition, you should use the drug consistently in order to get the maximum therapeutic benefit from it.

Before taking this drug, you should inform your pharmacist or doctor if you have an allergic reaction to it, to valproate sodium or divalproex, or if you have any other allergies in general. Valproic acid should not be used if you have or have had the following medical history: a tendency for low body water or dehydration, kidney disease, liver disease, pancreatitis, certain metabolic disorders like urea cycle disorder, or poor nutrition. Also, if you're undergoing minor or major surgery, tell your surgeon or dentist that you are taking this drug.

This drug is known to cause drowsiness and concentration problems, so use caution when engaging in activities that require clear vision or alertness, such as driving or operating heavy machinery. Conversely, limit your alcohol intake, because it may aggravate the lowered attentiveness side effect. Caution is also advised for the elderly when using this drug, because they may be more susceptible to its side effects, especially sleepiness and tremors.

This medication is known to cause birth effects, so it's obviously not recommended for use during pregnancy at any time. Talk to your designated healthcare specialist about the risks and benefits of this drug if you're planning to get pregnant. However, if you become pregnant while under valproic acid treatment, contact your doctor immediately as well. Prenatal care and tests for spinal cord defects will probably follow. The medication is known to pass into breast milk, so even though there have been no reports of harm to nursing babies, you need to consult your physician before breastfeeding.

The most typical side effects for this drug include weight changes, unsteadiness, shakiness or tremors, ringing in the ears, change in menstrual periods, blurred or double vision, hair loss, drowsiness, dizziness, and diarrhea. If any of these symptoms continue or worsen, contact your pharmacist or physician immediately.

If any of these serious side effects occur, report it to your doctor quickly: signs of infection like fever and persistent sore throat, mental or mood changes, uncontrolled eye movement or nystagmus, swelling of the hands or feet, fast and irregular heartbeat, easy bruising, unexplained bleeding, and chest pain.

Valproic acid has the following structural formula:

Chemical structure of valproic acid


• Molecular formula of valproic acid is C8H16O2
• Chemical IUPAC Name is 2-propylpentanoic acid
• Molecular weight is 144.211 g/mol
Valproic acid available : 250mg tablets

Brand name(s): Alti-Valproic, Bruceine D, Convulex, Delepsine, Depakene, Depakine, Deproic, Epilex, Epilim, Epival, Ergenyl, Mylproin, Myproic Acid, Sprinkle, Valcote, Valparin, Valproate, Valproato, Valproatum

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