is a brand name for the drug which goes by the generic name verapamil
. It belongs to a group of medications called calcium
blockers. It works by relaxing the muscles of your heart
and blood vessels
to allow for the passage of more blood
volume. It is given in extended release tablets, taken once a day at bedtime, for the treatment of high blood pressure
, or hypertension
, and for the treatment of chronic angina, or chest pains, and certain heart rhythm disorders. It may be used alone or in conjunction with other medications.
Very serious side effects are rare with Verapamilo treatment. Some of the most common side effects include swelling
in the legs
and feet, dizziness
and fatigue, all of which occur in a very small percentage of patients. Other side effects can include blockage of the atria, cough
, irregular or fast heartbeat, headache
, congestive heart failure
, low blood pressure, sleep disturbances, thirst, eye irritation, memory loss, depression
, tingling or numbness, ringing in the ears, or tremor. You may also experience loss of appetite
, abnormal gait, constipation
, nosebleeds, impotence, muscle cramps, runny nose
, weight gain, dry mouth
, sensitivity to light, frequent urination
at night, development of breast
tissue in men, skin discoloration, itchy skin, low white blood cell count, and peeling skin. You should call your doctor immediately if you have any of the following: fast or slow heartbeats, dark urine or clay-colored stools, jaundice, fever
, sore throat or headache with a severe blistering, peeling, and red skin rash.
Some drugs do not interact well with Verapamilo. If you are taking digoxin
, theophyline, carbamazepine
, or a beta-blocker, you may not be allowed to begin a course of treatment with Verapamilo. You should also be cautious if you are taking lithium; Verapamilo can reduce the levels of this drug in your blood. If you are taking any of these, your doctor and you may have to decide whether to adjust your dosages of Verapamilo or to pursue another course of treatment.
You should not take Verapamilo if you suffer from certain heart conditions, including “sick sinus
syndrome,” or “AV block,” unless you have a pacemaker, or if you have recently had a heart attack
. You should also make sure to let your doctor know if you are taking any other drugs, including over the counter or herbal medications, or if you have kidney
disease, or congestive heart failure.
Verapamilo is in Pregnancy Category C, which means that it is not known whether it is harmful to a pregnancy or to the development of a fetus. There have been no conclusive studies done in pregnant women, so you should use caution when taking Verapamilo if you are pregnant or planning to become pregnant. It is known, however, that Verapamilo passes into breast milk, so if you are breastfeeding a child, you should discontinue using Verapamilo. If you plan to continue using Verapamilo, you should explore other options for feeding your baby. Verapamilo has not been evaluated for use in children.
Verapamilo has the following structural formula:
• Molecular formula of verapamilo is C27H38N2O4
• Chemical IUPAC Name is 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]- 2-(1-methylethyl)pentanenitrile
• Molecular weight is 454.602 g/mol
• Verapamilo available : 40mg tablets, 80mg tablets, 120mg tablets