Wellbatrin is the brand name for a bupropion. It is prescribed for the treatment of major depressive disorder. The signs of this disorder include depression or loss of interest or ability to feel pleasure, in addition to at least five of the following: change in weight or appetite, sleeping too little or too much, increased tiredness, feelings of guilt or worthlessness, slowed thinking or inability to concentrate, thinking about suicide or attempting suicide. Wellbatrin is given in tablets to treat both acute episodes of depression and for long term stability.
The most serious warning given for the use of Wellbatrin is the increased risk for suicidal thinking and behavior in children, adolescents, and young adults. This risk is not increased in adults over the age of twenty-four years, and in fact decreases in adults over the age of sixty-five. However, depressive disorder itself is a major risk factor for suicidal thoughts and behavior, and should not be left untreated. Young patients taking Wellbatrin should be monitored carefully by health care providers and family members for signs of suicidal thoughts and behavior. If any are observed, seek help immediately.
Other side effects commonly experienced by those taking Wellbatrin included agitation, dry mouth, inability to sleep, headaches including migraines, nausea or vomiting, constipation, and tremor, or trembling in the hands. These side effects are usually and sometimes go away after your body becomes accustomed to the drug. Other infrequent or rare side effects can include swelling, chest pain, shortness of breath, heart attack, hair loss or excessive hair growth, dry skin, flushing, gynecomastia, difficulty swallowing, colitis, gastrointestinal bleeding, and stomach ulcer. In infrequent or rare cases, some people experience difficulties of the reproductive system such as vaginal irritation, swelling of the testicles, painful erection, difficulty ejaculating or painful ejaculation, pelvic infection, early menopause, ovarian disorder, increased sexual drive, inability to achieve orgasm, or pain during sexual intercourse. Other possible but rare side effects can include the need to urinate frequently at night, urinary tract infections, painful urination, involuntary urination, inflammation of the bladder, anemia, lack of coordination, memory impairment, psychosis, mood instability, dizziness, grinding of the teeth, toothaches, inflammation of the tongue, pneumonia, pulmonary embolism, double vision, flu-like symptoms, body odor, fever, high blood pressure, pain in the joints or muscles, high or low blood sugar, liver damage, low white blood cell count, aggression, coma, delirium, paranoia, involuntary movements, rash or deep red bumps under the skin, or ringing in the ears. Keep in mind, most of these effects occur in fewer than one in a hundred, or even one in a thousand people who take Wellbatrin.
Wellbatrin has been tested on pregnant women, and no evidence of fetal malformations or other harm has been observed. However, further studies are needed, so a pregnant woman should only take Wellbatrin during pregnancy if there is a clear necessity and the benefits outweigh the risks. It is known that Wellbatrin passes into breast milk, and may cause adverse effects to a nursing baby.
Wellbatrin has the following structural formula:
• Molecular formula of wellbatrin is C13H18ClNO
• Chemical IUPAC Name is 1-(3-chlorophenyl)-2-tert-butylamino-propan-1-one
• Molecular weight is 239.741 g/mol
• Wellbatrin available : 75mg tablets, 100mg tablets
Generic name: Bupropion
Brand name(s): Wellbutrin, Wellbutrin SR, Zyban
Review published on: 16 February 2008
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