is an analgesic, or pain reliever, and is used to treat pain that is moderate to severe. It is made from a combination of paracetamol
and comes in tablets.
Zaldiar is a well-tolerated drug, and has very few side effects. The side effects that do occur are not frequent, but can include constipation
, sleepiness, diarrhea
, increase in sweating and loss of appetite
. Other side effects can include prostatic disorder, anxiety
, weakness, euphoria, rash, nervousness, itchy skin, fatigue, dizziness
, flushing, insomnia
, tremor, heartburn
, abdominal pain, and dry mouth
. Other possible side effects occur in fewer than 1% of patients, but can include chest pain
of the tongue
, loss of consciousness, high blood pressure
, low blood
pressure, convulsions, migraine
, difficulty urinating, ringing in the ears, irregular heart
beat, abnormal liver
function, weight gain, amnesia, depression
, impotence, or anemia
One more serious risk of Zaldiar is that in some cases, seizures have been reported in those taking one of its ingredients, tramadol. Seizures have been reported in those taking normal doses, and the risk increases if you take more than the recommended amount. This seizure risk can also be increased if you are taking selective serotonin reuptake inhibitors (SSRI antidepressants or anorectics), tricyclic antidepressants or other tricyclic compounds, or any other opiods. Other medications that put you at higher risk for seizures if you are taking them with tramadol include MAO inhibitors, neuroleptics, or any other drugs that in themselves reduce your seizure threshold.
There are also other conditions that may cause you to react badly with Zaldiar. Some people have been known to have serious, even fatal, allergic reactions
, especially after the first dose. Other allergic reactions can include hives
, chest pains, and serious skin conditions. If you are at risk for respiratory depression, you should consider using a non-opiod pain reliever; respiratory difficulties may be exacerbated. In addition, if you have a head injury or other intracranial pressure you should use Zaldiar with caution. Since Zaldiar can cause drowsiness or dizziness, you should not use it before driving or operating heavy machinery until you know for sure that it will not impair you in these situations. You should not use Zaldiar at the same time as alcohol, and people who have impaired liver function should not take it. You should also not use Zaldiar along with other medications that include paracetamol.
Zaldiar belongs to Pregnancy Category C, which means that it has not been shown to cause birth defects in unborn babies. However, those conclusions are based upon animal studies, and no well-researched studies have been done on human subjects. Zaldiar is also not recommended for nursing mothers because its safety has not been established for newborns and infants. In some cases, seizures, withdrawal symptoms, and stillbirth have been reported in newborns, but again, this has not been thoroughly studied. Zaldiar is not recommended for children under age 12. Caution should be used when determining dosage for people over age of 65.
• Molecular formula of zaldiar is C16H25NO2
• Chemical IUPAC Name is 2-(dimethylaminomethyl)-1-(3-methoxyphenyl)-cyclohexan-1-ol
• Molecular weight is 263.375 g/mol
• Zaldiar available : 37.5mg tablets