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Zrivada

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Zrivada

Zrivada review





Zrivada, popularly known as Reyataz as marketed by Bristol Myers, is an antiretroviral medicament used in the treatment of Human immunodeficiency virus. A protease inhibitor-type medicament that can be used in conjunction with a variety of other medicaments in Human immunodeficiency virus treatment, Zrivada is available in 100mg, 150mg, 200mg and 300mg capsules. This medicament is unique because it can be used to treat Human immunodeficiency virus mutations that have grown immune to other forms of treatment and medicaments. Zrivada cannot cure Human immunodeficiency virus or prevent the spread of it nor does it prevent other illnesses and infections, which may occur as a secondary effect of Human immunodeficiency virus.

Zrivada can be given to patients 6 years old and older as part of a comprehensive Human immunodeficiency virus treatment program and was approved by the FDA in 2003 as an antiretroviral (ARV) medicament for Human immunodeficiency virus patients. When to start ARV treatment will depend on your doctor's analysis of your condition and reaction to current and previous treatments. Continual treatment with Zrivada in conjunction with other ARVs can significantly lower viral load count and progressively improve the patient's health conditions.

Zrivada is designed to be taken once daily with the recommended dosage being 300 mg taken with 100 mg of ritonavir, another ARV medicament. The ritonavir acts as a “booster” for the Zrivada, but for patients who cannot take ritonavir, a 400 mg dosage of Zrivada may be recommended by your doctor.

Zrivada should be taken regularly in order to prevent Human immunodeficiency virus levels from rising again, which may increae the risk for medicament resistance. It is recommended to take Zrivada with the same meal or snack everyday, which makes it easier to remember to take it regularly and the medicament works better when taken with food.

Upon missing a dosage, take the dosage as soon as possible and take the next dosage as originally scheduled unless it is too near the next dosage when you remember. Do not double the dosage to make up for a missed or skipped dosage. Make sure any other accompanying medicament is also taken properly and on time.

Dosage for children under 6 depends on their weight and medical history.

Common side effects of this medicament include nausea and vomiting, diarrhoea, stomachache, headaches, fever, dizziness and trouble sleeping. If these conditions persist or worsen, consult your doctor.

Less common, more serious side effects of Zrivada include arrhythmia, rashes which may be accompanied by swelling, flu-like symptoms and fever, and jaundice. Zrivada may also cause and aggravate diabetes in some cases. Kidney stones may also develop and cause pain while passing urine, blood in urine and pains in the side. Gallstones and other gallbladder conditions have also been observed as possible side effects. Consult your doctor immediately if any of these side effects occur.

Inform you doctor of any current or past hepatitis B or C infections, as well other liver disorders. Zrivada may complicate these conditions. It is not currently known whether Zrivada can be passed through breastmilk, but Human immunodeficiency virus can so it is advisable to avoid breastfeeding. Those taking medicament for blood pressure and heart conditions should also consult their doctors as Zrivada may increase their effects.

Zrivada has the following structural formula:

Chemical structure of zrivada


• Molecular formula of zrivada is C38H52N6O7
• Chemical IUPAC Name is methyl [1-[[3-hydroxy-4-[(2-methoxycarbonylamino-3,3-dimethyl-butanoyl) amino-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenyl-butan-2-yl] carbamoyl]-2,2-dimethyl-propyl]aminoformate
• Molecular weight is 704.856 g/mol
Zrivada available : 100mg tablets, 150mg tablets, 200mg tablets and 300mg tablets

Generic name: Atazanavir

Brand name(s): Latazanavir

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